Pharmacogenomics

Challenges and Opportunities in Therapeutic Implementation

Yui-Wing Francis Lam, Stuart R. Scott

• Publisher: Academic Press
• Year: 2018
• Print ISBN:
  9780128126264
• eBook ISBN:
  9780128126271
• Edition: 2
• Topic: Medicine
• Subtopic: Clinical Medicine

Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation, Second Edition, provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of pharmacogenomics from academic, regulatory, pharmaceutical, socio-ethical and economic perspectives. While emphasis is on the limitations in moving the science into drug development and direct therapeutic applications, this book also focuses on clinical areas with successful applications and important initiatives that have the ability to further advance the discipline. New chapters cover important topics such as pharmacogenomic data technologies, clinical testing strategies, cost-effectiveness, and pharmacogenomic education and practice guidelines. The importance of ethnicity is also discussed, which highlights phar,acogenomic diversity across Latin American populations.With chapters written by interdisciplinary experts and insights into the future direction of the field, this book is an indispensable resource for academic and industry scientists, graduate students and clinicians engaged in pharmacogenomics research and therapeutic implementation. - Provides viewpoints that focus on the scientific and translational challenges and opportunities associated with advancing the field of pharmacogenomics - Highlights progress in both the research and clinical areas of pharmacogenomics, as well as relevant implementation experience, challenges, and perspectives on direct-to-consumer genetic testing - Includes, where applicable, discussion points, review questions, and cases for self-assessment purposes and to facilitate in-depth discussion

Table of contents

• Cover image
• Title page
• Table of Contents
• Copyright
• Dedication
• List of Contributors
• Preface
• Chapter 1. Principles of Pharmacogenomics: Pharmacokinetic, Pharmacodynamic, and Clinical Implications
• Chapter 2. Governmental and Academic Efforts to Advance the Field of Pharmacogenomics
• Chapter 3. Incorporating Pharmacogenomics in Drug Development: A Perspective From Industry
• Chapter 4. Translating Pharmacogenomic Research to Therapeutic Potentials
• Chapter 5. Pharmacogenomics in Cancer Therapeutics
• Chapter 6. Pharmacogenetics in Cardiovascular Diseases
• Chapter 7. Pharmacogenomics in Psychiatric Disorders
• Chapter 8. Pharmacogenomic Considerations in the Treatment of HIV Infection
• Chapter 9. The Role of Pharmacogenomics in Diabetes
• Chapter 10. A Look to the Future: Pharmacogenomics and Data Technologies of Today and Tomorrow
• Chapter 11. The Importance of Ethnicity Definitions and Pharmacogenomics in Ethnobridging and Pharmacovigilance
• Chapter 12. Pharmacogenomics in Latin American Populations
• Chapter 13. Reactive, Point-of-Care, Preemptive, and Direct-to-Consumer Pharmacogenomics Testing
• Chapter 14. Economic Evaluation of Pharmacogenomic Testing: Lessons From Psychiatric Pharmacogenomics
• Chapter 15. Pharmacogenomics Education and Clinical Practice Guidelines
• Index