Proteomic Profiling and Analytical Chemistry
eBook - ePub

Proteomic Profiling and Analytical Chemistry

The Crossroads

  1. 264 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Proteomic Profiling and Analytical Chemistry

The Crossroads

About this book

Proteomic Profiling and Analytical Chemistry helps scientists without a strong background in analytical chemistry to understand basic analytical principles and apply them to proteomics profiling. In most proteomic profiling experiments, liquid chromatography is used; this method is also used widely in analytical chemistry. This book bridges the gap between overly specialized courses and books in mass spectrometry, proteomics and analytical chemistry. It also helps researchers with an analytical chemistry background to break into the proteomics field. Proteomic Profiling and Analytical Chemistry focuses on practical applications for proteomic research helping readers to design better experiments and to more easily interpret, analyze and validate the resulting data. Experimental aspects such as sample preparation, protein extraction and precipitation, gel electrophoresis, microarrays, dynamics of fluorescent dyes, and more are all covered in detail. - Covers the analytical consequences of protein and peptide modifications that may have a profound effect on how and what researchers actually measure - Includes practical examples illustrating the importance of problems in quantitation and validation of biomarkers - Helps in designing and executing proteomic experiments with sound analytics

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Yes, you can access Proteomic Profiling and Analytical Chemistry by Pawel Ciborowski,Jerzy Silberring in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Genetics & Genomics. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Cover image
  2. Title page
  3. Table of Contents
  4. Copyright
  5. Preface
  6. 1. Introduction
  7. 2. Biomolecules
  8. 3. Fundamental Strategies of Protein and Peptide Sample Preparation
  9. 4. Protein Extraction and Precipitation
  10. 5. Immunoaffinity Depletion of High-Abundant Proteins for Proteomic Sample Preparation
  11. 6. Gel Electrophoresis
  12. 7. Quantitative Measurements in Proteomics
  13. 8. Proteomic Database Search and Analytical Quantification
  14. 9. Microarrays and Dynamics of Fluorescent Dyes
  15. 10. Design and Statistical Analysis of Mass Spectrometry-Based Quantitative Proteomics Data
  16. 11. Principles of Analytical Validation
  17. 12. Validation in Proteomics and Regulatory Affairs
  18. Index