Clinical Genome Sequencing

Psychological Considerations

Aad Tibben, Barbara B. Biesecker

• Publisher: Academic Press
• Year: 2019
• Print ISBN: 9780128133354
• eBook ISBN: 9780128133361
• Topic: Medicine
• Subtopic: Genetics in Medicine

Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine. - Features contributions from leading international researchers and practitioners versed in the psychosocial dimensions of genomic medicine implementation - Presents clinical case studies that support concept illustration, making this an invaluable reference for students, researchers, and clinicians looking for practical guidance in this important and multifaceted topic area - Details the current state of genomic testing, expectations of genome sequencing, patient consent, patient responses to sequencing data, uncertainties in genome sequencing, direct-to-consumer genome sequencing, and more

Table of contents

• Cover image
• Title page
• Table of Contents
• Copyright
• Dedication
• List of Contributors
• Chapter 1. Genetic Testing Expanded
• Chapter 2. Genome Sequencing and Individual Responses to Results
• Chapter 3. Consenting Patients to Genome Sequencing
• Chapter 4. Judgment and Decision Making in Genome Sequencing
• Chapter 5. Uncertainties in Genome Sequencing
• Chapter 6. Direct-to-Consumer Genetic Testing
• Chapter 7. Assessing the Psychological Impact of Next-Generation Sequencing Information in the Clinic: An Attempt to Map Terra Incognita?
• Chapter 8. Genetic Counseling and Genomic Sequencing
• Chapter 9. Genome Sequencing in Pediatrics: Ethical Issues
• Chapter 10. Genome Sequencing in Prenatal Testing and Screening: Lessons Learned From Broadening the Scope of Prenatal Genetics From Conventional Karyotyping to Whole-Genome Microarray Analysis
• Chapter 11. Clinical Genetic Testing and Counseling in Psychiatry
• Chapter 12. Opportunistic Genomic Screening: Ethical Exploration
• Chapter 13. Summary of Key Areas for Research
• Index