
- 518 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Fundamentals of Molecular Structural Biology
About this book
Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche.- Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advances- Addresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biology- Presents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease
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Information
Table of contents
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- About the Author
- Preface
- Acknowledgments
- Chapter 1: Introduction—A historical perspective
- Chapter 2: Mathematical tools
- Chapter 3: Physical basis of chemistry
- Chapter 4: Chemical basis of biology
- Chapter 5: Biomacromolecules
- Chapter 6: Structure analysis and visualization
- Chapter 7: Protein folding
- Chapter 8: DNA synthesis: Replication
- Chapter 9: Transcription
- Chapter 10: RNA processing
- Chapter 11: Translation
- Chapter 12: DNA damage and repair
- Chapter 13: Recombination
- Chapter 14: Membrane structure and function
- Chapter 15: Fundamentals of structural genomics
- Chapter 16: Cell signaling and systems biology
- Chapter 17: Macromolecular assemblies
- Chapter 18: Computational molecular biology
- Index