Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy
eBook - ePub

Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy

  1. 368 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy

About this book

Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. - Provides a fundamental understanding of the basic functions of growth factors and their receptors, describing how they are linked in biological processes - Aids the development of therapeutic treatments for cancer - Focuses on the interrelationships and convergence of growth factors and their receptors in development and pathogenesis and encourages greater cooperation and integration in the areas of developmental, cancer and cancer therapeutic research

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Yes, you can access Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy by G V Sherbet in PDF and/or ePUB format, as well as other popular books in Sciences biologiques & Biochimie. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Elsevier
Year
2011
Print ISBN
9780123878199

Table of contents

  1. Cover image
  2. Table of Contents
  3. Front-matter
  4. Dedication
  5. Copyright
  6. Preface
  7. Abbreviations
  8. Introduction
  9. 1. Convergence of Growth-Factor Signalling Pathways in Developmental Systems and Pathogenesis
  10. 2. Growth Factor Families
  11. 3. Growth Factors in Differentiation and Morphogenesis
  12. 4. Vascular Endothelial Growth Factor
  13. 5. Hepatocyte Growth Factor
  14. 6. The Platelet-Derived Growth Factor Family
  15. 7. Nerve Growth Factors
  16. 8. Insulin-Like Growth Factors
  17. 9. Connective Tissue Growth Factor
  18. 10. Thrombospondins
  19. 11. Cytokines
  20. 12. Growth Factor and Hedgehog Signalling Pathways Meet in Developmental Systems
  21. 13. Epidermal Growth Factors and Their Signalling Systems
  22. 14. The Epidermal Growth Factor (EGF) Family
  23. 15. The Fibroblast Growth Factor Family
  24. 16. Intracellular Receptor Binding Growth Factors
  25. 17. The Androgens and Androgen Receptors in Development, Differentiation and Neoplasia
  26. 18. Vitamin D3 in Cell Proliferation, Apoptosis and Differentiation
  27. 19. Retinoids in Development and Pattern Formation
  28. 20. Oestrogens and Progesterone in Normal Physiology and Neoplasia
  29. 21. Glucocorticoid Signalling in Normal and Aberrant Physiology
  30. Epilogue
  31. References