Biophysical Characterization of Proteins in Developing Biopharmaceuticals
- 586 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Biophysical Characterization of Proteins in Developing Biopharmaceuticals
About this book
Biophysical Characterization of Proteins in Developing Biopharmaceuticals, Second Edition, presents the latest on the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure, this book explains the best way to achieve this goal using key methods commonly employed in the biopharmaceutical industry. This book will help today's industrial scientists plan a career in this industry and successfully implement these biophysical methodologies. This updated edition has been fully revised, with new chapters focusing on the use of chromatography and electrophoresis and the biophysical characterization of very large biopharmaceuticals.In addition, best practices of applying statistical analysis to biophysical characterization data is included, along with practical issues associated with the concept of a biopharmaceutical's developability and the technical decision-making process needed when dealing with biophysical characterization data.- Presents basic protein characterization methods and tools applicable to (bio)pharmaceutical research and development- Highlights the capabilities and limitations of each technique- Discusses the underlining science of each tool- Empowers industrial biophysical chemists by providing a roadmap for applying biophysical tools- Outlines the needs for new characterization and analytical tools in the biopharmaceutical industry
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Information
Table of contents
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Prefaces for the second edition
- List of abbreviations and symbols
- I. Proteins and biophysical characterization in the biopharmaceutical industry
- II. The selected biophysical tools in the biopharmaceutical industry
- III. Concluding remarks on the biophysical characterization of biopharmaceuticals
- Index