Molecular Approach to Cancer Management
eBook - ePub

Molecular Approach to Cancer Management

  1. 352 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Molecular Approach to Cancer Management

About this book

Molecular Approach to Cancer Management discusses molecular mechanisms of cancer initiation, growth and secondary spread, emphasizing how this information can be used to devise new modes of treatment of cancer, especially in combatting secondary spread. The book addresses the basic concepts relating to cancer biology, the genetic determinants, and the signal transduction cascades associated with tumor growth, EMT, stem cell maintenance and propagation, and invasion and metastasis. The salient features of the signaling systems that are amenable to targeted manipulation are emphasized to facilitate research and development in the design of novel therapies and for the planning of new trials.This book is the only unique volume with coverage of topics that target therapy. As such, it is a valuable source for cancer researchers, molecular oncologists and members of the biomedical field who are interested in knowing more about molecular approaches to cancer therapy.- Covers all relevant topics with a defined aim of targeted therapy- Encompasses the basic aspects of cancer invasion and metastasis- Discusses signaling systems operating in normal cells and their deregulation in cancer cells- Directs attention to the foci in signaling systems that can be targeted with a new and conventional drug-based approach

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Yes, you can access Molecular Approach to Cancer Management by Gajanan V. Sherbet in PDF and/or ePUB format, as well as other popular books in Medicine & Oncology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2017
Print ISBN
9780128128961
eBook ISBN
9780128128978
Topic
Medicine
Subtopic
Oncology

Table of contents

  1. Cover image
  2. Title page
  3. Table of Contents
  4. Copyright
  5. Dedication
  6. Preface
  7. Abbreviations
  8. Introduction
  9. Chapter 1. Modulation of Growth Factor Signalling in Targeted Therapy: Role of the Epidermal Growth Factor Family and Their Receptors
  10. Chapter 2. The TGF-β Family Accessory Type III Receptor Function in Cancer Progression
  11. Chapter 3. Insulin-Like Growth Factor Signalling as a Target to Control Tumour Progression
  12. Chapter 4. Angiogenesis in Neoplasia and Anti-Angiogenesis Strategy in the Control of Tumour Growth and Metastasis
  13. Chapter 5. On the Trail of TRAIL (TNF-Related Apoptosis Inducing Ligand) in Tumour Growth and Angiogenesis
  14. Chapter 6. Hedgehog (Hh) Signalling in EMT (Epithelial Mesenchyme Transition), CSCs (Cancer Stem Cells) and Angiogenesis
  15. Chapter 7. Hippo Signalling in Cell Proliferation, Migration and Angiogenesis
  16. Chapter 8. Notch Signalling in Carcinogenesis
  17. Chapter 9. Canonical and Non-Canonical Activation of NF-κB in Tumorigenesis
  18. Chapter 10. Tumour Suppression and Inhibition of Angiogenesis by TXNIP (Thioredoxin Interacting Protein)
  19. Chapter 11. Cyclooxygenase-2 Inhibitors Suppress EMT, CSCs and Angiogenesis
  20. Chapter 12. Endogenous Inhibitors of Angiogenesis
  21. Chapter 13. Stem Cells in Cancer Therapy
  22. Chapter 14. Inhibitor of DNA-Binding Proteins in Angiogenesis
  23. Chapter 15. Small Molecule Inhibitors of Angiogenesis and Cell Proliferation
  24. Chapter 16. Suramin and Polysulphonated Naphthylureas as Angiogenesis Inhibitors
  25. Chapter 17. The Anti-Cancer Potential of Flavonoids
  26. Chapter 18. Selenoproteins in Cancer Control
  27. Chapter 19. Control of Tumour Growth and Angiogenesis by Thalidomide and Its Analogues
  28. Chapter 20. Metformin and Its Anti-Tumour Attributes
  29. Chapter 21. Statins in Cancer Biology
  30. Chapter 22. Are There Gains to be Made in Exploring Anthrax Lethal Toxin (LeTx) as a Tumour and an Angiogenesis Inhibitor?
  31. Chapter 23. The HMG (High Mobility Group) Proteins in Cancer Progression
  32. Chapter 24. MTAs in EMT Activation and Tumour and Metastasis Promotion
  33. Chapter 25. S100A4 Has Potential Benefits as a Therapeutic Target
  34. Chapter 26. Notable Approaches to Cancer Immunotherapy
  35. The Epilogue
  36. References
  37. Index