Delivery System Handbook for Personal Care and Cosmetic Products

Technology, Applications and Formulations

Meyer Rosen

• Publisher: William Andrew
• Year: 2005
• eBook ISBN: 9780815516828
• Topic: Technik & Maschinenbau
• Subtopic: Dermatologie

Novel delivery systems designed to facilitate the use of ôfountain of youthö and other functional actives is an idea whose time has come. In a rapidly growing global market eager for products that really work, accelerating market pull forces and technology push have set the stage for this foundation text. This ômust haveö book has been carefully designed for training, development and synergistic technology transfer across the personal care, cosmetic and pharmaceutical industries. It is not only intended for scientists and technologists but will also be of high interest to market development and business personnel. This book will cause a breakthrough in effective interaction among technology and marketing. It is a showcase for understanding, using and marketing the technology of why and how delivery systems work as well as current, emerging/potential applications and working formulations. Each chapter is written by one or more experts in the field. A wide range of companies serving the global marketplace are represented. These companies offer numerous types of delivery systems containing highly desirable functional actives, delivery system technology development services, and opportunities for technology licensing, mergers and acquisitions. A unique feature of the book is the use of Mind MapÖ technology to capture and present the essence of the thinking of over 80 authors in a ôBook-at-a-Glanceö Executive Overview section. This section has been specifically designed to empower decision making leading to the development of innovative product differentiation in a global context.

Part I

Introduction

1 The Delivery System Movement

Meyer R. Rosen

Interactive Consulting, Inc., East Norwich, New York

1.1. Introduction

1.2. The “Eureka!” Moment

1.3. The Birth of Ideas

1.4. What is a Delivery System?

1.4.1. Factors Affecting the Efficacy of a Delivery System

1.4.2. For What Application Areas are Delivery Systems Useful?

1.5. The Philosophy Behind This Book.

1.5.1. What You Should LOOK FOR As You Read

1.6. Using the “Maps”

1.1 Introduction

After about three years in the making, it is my pleasure and privilege to introduce you to what I assert will become the basic textbook defining the foundation of the Delivery System Movement.

In the last several years, the personal care industry has recognized that it must go beyond the simple identification of useful actives that provide the basis for novel claims, features, and benefits. Further, the industry has come to recognize that a pinch of something good, mentioned on the label for its advertising value, or its good “story,” just doesn’t cut it any more with real people in the aging, baby boomer population. Further, having too low a level of a high profile ingredient is no longer appropriate for their smoother skinned offspring who want to do everything they can to avoid the wrinkled appearance of their elders.

Some of the issues associated with the industry’s recognition of the need to move to a higher ground include providing protection of functional actives from processing, environmental, and formulation stressors. Fortunately, these needs are timely since they correspond with the emergence of a technology platform to provide solutions for these issues (i.e., the new “Science of Delivery Systems”). This science relies upon a whole range of new and existing technologies. These technologies are evolving at a rapid rate and address the need for novel approaches to carry actives within formulations and successfully deliver them to substrates like skin and hair. These methodologies provide technology that controls when the actives should be delivered, where they should be delivered, how they should be delivered, and enable their delivery at an optimal rate.

Delivery onto, and into, the substrate at some useful concentration, in a timely fashion, under appropriate use and application conditions is of critical importance. Control of an active’s release, where and when it will do the most good, is indeed becoming a critical issue. Stimulation triggers like pH, temperature, shear, and enzymes are all under investigation to allow the formulation chemist more complete control of this area. This approach will significantly impact the design of future generations of personal care systems.

The challenges described above are being broadly addressed by a wide range of supplier and formulator companies. During the research phase of this book, I contacted over 150 companies doing work in this area. It became apparent that numerous opportunities for technology transfer exist at the interface among the Pharmaceutical (i.e., Drugs), Personal Care (i.e., Cosmeceuticals & Functional Actives), Food (i.e., Nutraceuticals) and the Industrial arenas. While the title of this book is Delivery System Handbook for Personal Care and Cosmetic Products, there is much of interest to those individuals responsible for research, marketing, and business in these other markets. I invite you to look for ideas in your area even though it may not specifically be Personal Care. There are many nuggets of gold just waiting to be transferred to areas outside of Personal Care, especially if you stay open as you read and take what you get. The best ideation emerges from a “silent synthesis” of what is on the page and what is in your mind. This is especially true if you read the book having put at stake your commitment to generate new ideas and applications in your own field.

As with any complex issue, numerous technical approaches have evolved, and continue to evolve, to solve the emerging challenges. With each jump in technology, a range of new capabilities has become apparent. These capabilities represent an ever-widening choice of approaches for formulators as well as new opportunities for achieving truly effective, consumer-perceivable benefits.

This bo...

Table of contents

• Cover image
• Title page
• Table of Contents
• Copyright
• Dedication
• Contributing Authors
• Contributing Companies and Universities
• Series Editor’s Preface
• Preface
• Acknowledgments
• Part I: Introduction
• Part II
• Part III: Crossing the Barrier
• Part IV: Encapsulation
• Part V: Liposomes
• Part VI: Particles
• Part VII: Emulsions
• Part VIII: Foams
• Part IX: Structured Systems
• Part X: Silicones
• Part XI: Starch-Based Systems
• Part XII: Activated Delivery Systems
• Part XIII: Substrate-Based Systems
• Part XIV: Specific Ingredient Delivery
• Part XV: Efficacy and Safety
• Part XVI: Marketing by Design and Advertising Analysis
• Glossary
• Suppliers/Vendors
• Trademarks
• Index