Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics

Carl Faingold, Hal Blumenfeld

• Publisher: Academic Press
• Year: 2013
• Print ISBN:
  9780124158047
• eBook ISBN:
  9780124158641
• Topic: Medicine
• Subtopic: Neurology

Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: - How the brain carries out important tasks via networks - How these networks interact in normal brain function - Major mechanisms that control network function - The interaction of the normal networks to produce more complex behaviors - How brain disorders can result from abnormal interactions - How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. - Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant - Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders - Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Table of contents

• Cover image
• Title page
• Table of Contents
• Dedications
• Copyright
• List of Contributors
• Chapter 1. Introduction to Neuronal Networks of the Brain
• Chapter 2. Network Models of Absence Seizures
• Chapter 3. Functional Magnetic Resonance Imaging in Epilepsy: Methods and Applications Using Awake Animals
• Chapter 4. Network Experimental Approaches: Inactivation, Microinjection, Neuronal Stimulation, and Recording
• Chapter 5. Network Experimental Approaches: Ex vivo Recording
• Chapter 6. Network Imaging
• Chapter 7. Network Control Mechanisms: Cellular Inputs, Neuroactive Substances, and Synaptic Changes
• Chapter 8. Volume Transmission and the Russian-Doll Organization of Brain Cell Networks: Aspects of Their Integrative Actions
• Chapter 9. Electrophysiological Mechanisms of Network Control: Bursting in the Brain—From Cells to Networks
• Chapter 10. Network Control Mechanisms—Cellular Milieu
• Chapter 11. Neuronal Network Mechanisms—Sex and Development
• Chapter 12. Astrocytic Regulation of Synapses, Neuronal Networks, and Behavior
• Chapter 13. The Fear Memory Network
• Chapter 14. Orchestration of the Circadian Clock Network by the Suprachiasmatic Nucleus
• Chapter 15. mTOR Signaling in Cortical Network Development
• Chapter 16. Network Control Mechanisms—Synaptogenesis and Epilepsy Development
• Chapter 17. The Brain and Spinal Cord Networks Controlling Locomotion
• Chapter 18. The Brainstem Respiratory Network
• Chapter 19. Visual Network
• Chapter 20. Auditory Neuronal Networks and Chronic Tinnitus
• Chapter 21. Consciousness and Subcortical Arousal Systems
• Chapter 22. Networks of Normal and Disordered Sleep
• Chapter 23. Networks for the Modulation of Acute and Chronic Pain
• Chapter 24. Networks in Mood and Anxiety Disorders
• Chapter 25. Neuronal Networks and Therapeutics in Neurodegenerative Disorders
• Chapter 26. Neuronal Networks in Epilepsy: Comparative Audiogenic Seizure Networks
• Chapter 27. Physiological and Pathophysiological Expansion of Neuronal Networks
• Chapter 28. Neuronal Network Plasticity and Network Interactions are Critically Dependent on Conditional Multireceptive (CMR) Brain Regions
• Chapter 29. Neuronal Network Interactions in the Startle Reflex, Learning Mechanisms, and CNS Disorders, Including Sudden Unexpected Death in Epilepsy
• Chapter 30. Emergent Properties of Neuronal Networks
• Chapter 31. Neuronal Network Involvement in Stimulation Therapies for CNS Disorders
• Chapter 32. Neuronal Network Effects of Drug Therapies for CNS Disorders
• Chapter 33. Future Trends in Neuronal Networks—Selective and Combined Targeting of Network Hubs
• Color Plates
• Index