Systems Biomedicine
eBook - ePub

Systems Biomedicine

Concepts and Perspectives

  1. 448 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

Systems Biomedicine

Concepts and Perspectives

About this book

Systems biology is a critical emerging field that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems.Systems Biomedicine is organized around foundations, computational modeling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon.- Organized to reflect the important distinguishing characteristics of systems strategies in experimental biology and medicine- Provides precise and comprehensive measurement tools for constructing a model of the system and tools for defining complexity as an experimental dependent variable- Includes a thorough discussion of the applications of quantitative principles to biomedical problems

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Yes, you can access Systems Biomedicine by Edison T. Liu,Douglas A. Lauffenburger in PDF and/or ePUB format, as well as other popular books in Sciences biologiques & Biochimie. We have over one million books available in our catalogue for you to explore.

Information

Table of contents

  1. Cover image
  2. Table of Contents
  3. Copyright
  4. Overview
  5. Chapter 1. Foundations for Systems Biomedicine
  6. Chapter 2. Genomic Technologies for Systems Biology
  7. Chapter 3. Proteomics Technologies
  8. Chapter 4. Cellular Regulatory Networks
  9. Part I. Transcriptional Networks
  10. Part II. Protein Phosphorylation Networks
  11. Chapter 5. The Interface of MicroRNAs and Transcription Factor Networks
  12. Chapter 6. Protein Networks in Integrin-Mediated Adhesions
  13. Chapter 7. Systems Biology and Stem Cell Biology
  14. Chapter 8. Computational Challenges in Systems Biology
  15. Chapter 9. High-level Modeling of Biological Networks
  16. Chapter 10. Systems Analysis for Systems Biology
  17. Chapter 11. The Virtual Cell Project
  18. Chapter 12. Software Tools for Systems Biology
  19. Chapter 13. Physiome Mark-up Languages for Systems Biology
  20. Chapter 14. Systems Approaches to Developmental Patterning
  21. Chapter 15. Applications of Immunologic Modeling to Drug Discovery and Development
  22. Chapter 16. Systems Pharmacology in Cancer
  23. Chapter 17. Systems Biology in Drug Discovery
  24. Chapter 18. Quantitative Biology and Clinical Trials
  25. Index