
- 560 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Origin and Evolution of Viruses
About this book
New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases.- NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution- UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups- SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts
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Table of contents
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface to the Second Edition
- Preface to the First Edition
- Chapter 1: Early Replicons: Origin and Evolution
- Chapter 2: Structure and Evolution of Viroids
- Chapter 3: Mutation, Competition, and Selection as Measured with Small RNA Molecules
- Chapter 4: Viral Quasispecies: Dynamics, Interactions, and Pathogenesis
- Chapter 5: Comparative Studies of RNA Virus Evolution
- Chapter 6: Nucleic Acid Polymerase Fidelity and Viral Population Fitness
- Chapter 7: The Complex Interactions of Viruses and the RNAi Machinery: A Driving Force in Viral Evolution
- Chapter 8: The Role of the APOBEC3 Family of Cytidine Deaminases in Innate Immunity, G-to-A Hypermutation, and Evolution of Retroviruses
- Chapter 9: Lethal Mutagenesis
- Chapter 10: Evolution of dsDNA Tailed Phages
- Chapter 11: More About Plant Virus Evolution: Past, Present, and Future
- Chapter 12: Mutant Clouds and Bottleneck Events in Plant Virus Evolution
- Chapter 13: Retrovirus Evolution
- Chapter 14: Intra-host Dynamics and Evolution of HIV Infection
- Chapter 15: The Impact of Rapid Evolution of Hepatitis Viruses
- Chapter 16: Arbovirus Evolution
- Chapter 17: Evolution and Variation of the Parvoviruses
- Chapter 18: Genome Diversity and Evolution of Papillomaviruses
- Chapter 19: Origin and Evolution of Poxviruses
- Chapter 20: Molecular Evolution of the Herpesvirales
- Chapter 21: The Widespread Evolutionary Significance of Viruses
- Index