Biochemistry and Oral Biology

A. S. Cole, J. E. Eastoe

• Publisher: Butterworth-Heinemann
• Year: 2014
• Print ISBN: 9780723617518
• eBook ISBN: 9781483183718
• Edition: 2
• Topic: Biological Sciences
• Subtopic: Biology
• Index: Biological Sciences

Biochemistry and Oral Biology presents a unique exposition of biochemistry suitable for dental students. It discusses the structural basis of metabolism and the general principles of nutrition. It addresses the soft tissues, hard tissues, and the biology of the mouth. Some of the topics covered in the book are the free radical production; scope of biochemistry; characteristics of atoms; structure and properties of water; molecular building materials; ionization of proteins; affinity chromatography of proteins; structural organization of globular proteins; classification of enzymes; and biochemically important sugar derivatives. The naturally occurring fatty acids are fully covered. The nucleic acid components are discussed in detail. The text describes in depth the energy equivalents of different nutrients. The physiological effects of dietary fiber vitamin D deficiency are completely presented. A chapter is devoted to the alternative methods of fluoride administration and description of vitamins. The book can provide useful information to dental students, and researchers.

Section 1

Some preliminary considerations

Outline

Chapter 1: Introduction

Chapter 2: From atoms to molecules

Chapter 3: The molecular environment

Chapter 1

Introduction

Publisher Summary

The aims of biochemistry are to describe the nature of living forms and living processes in terms of chemistry and physics. Biochemists believe that the existence and activities of living organisms are explained on the basis of the interaction of their component molecules. These are divided very broadly into two groups, namely, small molecules and macromolecules. The main types of macromolecule are proteins, nucleic acids, and polysaccharides, all of which are long, chain-like molecules built up from a large number of linked subunits. These biopolymers tend to associate into still larger complexes with other molecules that may or may not be of the same type. The small molecules act not only as the building units from which macromolecules are synthesized but also as sources of energy, messengers, and regulators. Macromolecules are the essential basis of the elaborate structures in and around which the life processes occur; they also control and regulate these processes. Thus, macromolecules are responsible for the energy exchanges and chemical reactions that comprise metabolism for the irritability that enables the organism to respond to changes in its environment, for mobility, and for reproduction. The aims, attitudes, and techniques of biochemistry are as relevant to dentistry as to medicine or any other aspect of biology. Only when the normal structures of the mouth and their development and reactions are understood is it possible to appreciate the true nature of dental disease. All disease has a biochemical basis regardless of whether its origin is nutritional or genetic or it is caused by an infectious or toxic agent.

The scope of biochemistry

The aims of biochemistry are to describe the nature of living forms and living processes in terms of chemistry and physics. Biochemists believe that the existence and activities of living organisms can be explained on the basis of the interaction of their component molecules. These may be divided very broadly into two groups, namely small molecules and macromolecules.

The main types of macromolecule are proteins, nucleic acids and polysaccharides, all of which are long, chain-like molecules built up from a large number of linked subunits. These biopolymers tend to associate into still larger complexes with other molecules which may or may not be of the same type. The small molecules act not only as the building units from which macromolecules are synthesized but also as sources of energy, messengers and regulators. Macromolecules are the essential basis of the elaborate structures in and around which the life processes occur; they also control and regulate these processes. Thus macromolecules are responsible for the energy exchanges and chemical reactions that comprise metabolism, for the irritability which enables the organism to respond to changes in its environment, for mobility and for reproduction.

Since molecules do not function alone but by interaction with other molecules, living p...

Table of contents

• Cover image
• Title page
• Table of Contents
• Inside Front Cover
• Copyright
• Foreword
• Preface to the second edition
• Preface to the first edition
• Units
• Section 1: Some preliminary considerations
• Section 2: Molecular architecture – the building materials
• Section 3: Nutrition – sources of energy and materials
• Section 4: Molecular organization and interactions
• Section 5: Control processes
• Section 6: Soft tissues
• Section 7: Calcified tissues
• Section 8: Biology of the mouth
• Suggestions for further reading
• Index