Progress in Hodgkin's Disease

G. W. Richter, Kim Solez, G. W. Richter, Kim Solez

• Publisher: Academic Press
• Year: 2013
• Print ISBN: 9780123649331
• eBook ISBN: 9781483276045
• Topic: Medicine
• Subtopic: Diseases & Allergies

International Review of Experimental Pathology, Volume 33: Progress in Hodgkin's Disease summarizes the progress made in the diagnosis and understanding of the pathogenesis of Hodgkin's disease. The first half of this volume deals with diagnostic aspects, whereas the second half focuses on recent developments in the understanding of the pathogenesis of Hodgkin's disease. The book opens with a chapter on the differential diagnosis between Hodgkin's disease and non-Hodgkin's lymphomas, and provides guidelines on how to deal with the grey areas between these two groups of diseases. Separate chapters follow on the criteria for a prognostically relevant histological grading of the most common subtype of Hodgkin's disease; data on the nodular lymphocyte predominance subtype of Hodgkin's disease; and the various reagents used to define the immunophenotype of Reed-Sternberg cells. Subsequent chapters deal with potential mediators of lymphocyte agglutination to Reed-Sternberg cells; immunological alterations in Hodgkin's disease; molecular genetic studies into the pathogenesis of Hodgkin's disease; and results of studies on Hodgkin cell lines. This book provides data that go beyond those covered in textbooks in pathology and hematology and should be of interest to all pathologists and clinicians dealing with the diagnosis and management of Hodgkin's disease, as well as to lymphoma researchers.

Table of contents

• Cover image
• Title page
• Table of Contents
• Editorial Advisory Board
• Copyright page
• Contributors
• Preface
• Differential Diagnosis between Hodgkin’s Disease and Non-Hodgkin’s Lymphoma
• Diagnosis and Grading of Nodular Sclerosing Hodgkin’s Disease: A Study of 2190 Patients
• Lymphocyte-Predominance Hodgkin’s Disease
• Immunophenotype of Reed—Sternberg Cells
• The Nature and Function of the Hodgkin’s Cell Lectin and Its Role in Lymphocyte Agglutination
• Role of T Cells in the Pathogenesis of Hodgkin’s Disease
• Gene Analysis and Epstein—Barr Viral Genome Studies of Hodgkin’s Disease
• Hodgkin’s Disease: Analysis of Cell Line Data
• Index
• Contents of Recent Volumes