Biochemistry of Characterised Neurons

Neville N. Osborne

• Publisher: Pergamon
• Year: 2013
• Print ISBN:
  9780080215037
• eBook ISBN:
  9781483145532
• Topic: Biological Sciences
• Subtopic: Biophysics
• Index: Biological Sciences

Biochemistry of Characterised Neurons provides a report on the progress made in the analysis of the biology of specific neurons in the central nervous system. This book emphasizes the biochemical, morphological, and functional aspects of characterized neurons, including ways and sophisticated techniques of isolating them. This publication is divided into 11 chapters. The first chapter evaluates the relevance of working with single neurons. Chapters 2 to 6 discuss specific, characterized, invertebrate neurons containing one of the putative neurotransmitter substances. Chapter 7 deals with the biochemistry of a unique vertebrate (Torpedo) cholinergic system that enables pure cholinergic neuronal cell bodies and endings to be analyzed separately. The sensitive radiochemical procedures used to analyze transmitter substances and transmitter enzymes, and how they can be adapted to map the distribution of transmitters in individual neurons of Aplysia, are discussed in Chapter 8. Chapter 9 describes methods for the analysis of specific cells in the retina, while Chapters 10 and 11 focus on the analysis of proteins within defined neurons. This text is beneficial to biochemists and students interested in analyzing neurons.

Table of contents

• Cover image
• Title page
• Table of Contents
• Copyright
• Dedication
• Abbreviations
• PREFACE
• FOREWORD
• Chapter 1: VALIDITY OF SINGLE NEURON CHEMICAL ANALYSIS: CAN MICROCHEMISTRY HELP TO SOLVE THE “HARD” QUESTIONS OF MODERN NEUROBIOLOGY?
• Chapter 2: THE RETZIUS CELL OF THE LEECH HIRUDO MEDICINALIS
• Chapter 3: THE NEUROBIOLOGY OF A SEROTONERGIC NEURON
• Chapter 4: THE CHARACTERISED DOPAMINE NEURON IN PLANORBIS CORNEUS
• Chapter 5: OCTOPAMINE NEURONS IN THE LOBSTER
• Chapter 6: HISTAMINE-CONTAINING NEURONS IN APLYSIA
• Chapter 7: THE BIOCHEMISTRY OF TORPEDO CHOLINERGIC NEURONS
• Chapter 8: MICROASSAY OF BIOGENIC AMINES IN NEURONS OF APLYSIA. THE COEXISTENCE OF MORE THAN ONE TRANSMITTER MOLECULE IN A NEURON
• Chapter 9: PHYSIOLOGICAL AND BIOCHEMICAL STUDIES OF IDENTIFIED CELLS IN THE VERTEBRATE RETINA
• Chapter 10: GENE EXPRESSION AND PROTEIN METABOLISM IN INDIVIDUAL NEURONS OF APLYSIA
• Chapter 11: FUNCTION AND METABOLISM OF NEURONAL PROTEINS: COMPARISONS AMONG THE IDENTIFIED NEURONS OF APLYSIA
• SUBJECT INDEX