The Mouse in Biomedical Research
eBook - PDF

The Mouse in Biomedical Research

History, Wild Mice, and Genetics

,
  1. 352 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

The Mouse in Biomedical Research

History, Wild Mice, and Genetics

,

About this book

History, Wild Mice, and Genetics, the first volume in the four volume set, The Mouse in Biomedical Research, provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild mice. Genetics and genomics of the mouse are covered in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Maintenance of laboratory mice is described in chapters on breeding systems for various types of strains and stocks and genetic monitoring. Use of the mouse as a model system for basic biomedical research is described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulation. The information in Volume 1 serves as a primer for scientists new to the field of mouse research.

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Information

Publisher
Academic Press
Year
2006
eBook ISBN
9780080469065
Edition
2
Topic
Biological Sciences
Subtopic
Zoology
Index
Biological Sciences

Table of contents

  1. Front Cover
  2. The Mouse in Biomedical Research: History, Wild Mice, and Genetics
  3. Copyright Page
  4. Table of Contents
  5. List of Reviewers
  6. List of Contributors
  7. Foreword
  8. Preface
  9. Chapter 1. Building a Better Mouse: One Hundred Years of Genetics and Biology
  10. Chapter 2. Systematics of the genus Mus
  11. Chapter 3. The Secret World of Wild Mice
  12. Chapter 4. Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types
  13. Chapter 5. Mouse Strain and Genetic Nomenclature: an Abbreviated Guide
  14. Chapter 6. The Mouse Genome
  15. Chapter 7. Gene Mapping
  16. Chapter 8. Genetic Monitoring
  17. Chapter 9. Cytogenetics
  18. Chapter 10. Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man
  19. Chapter 11. Gamete and Embryo Manipulation
  20. Chapter 12. Chemical Mutagenesis in Mice
  21. Chapter 13. Gene-Specific Mutagenesis
  22. Chapter 14. Gene Transfer Studies Using Mouse Models
  23. Chapter 15. Mouse and Human Pluripotent Stem Cells
  24. Chapter 16. Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics
  25. Index
  26. Colour Plates