Plasticity in the Adult Brain: From Genes to Neurotherapy

M.A. Hofman, G.J. Boer, Eus JW Van Someren, J. Verhaagen, D.F. Swaab, A.J.G.D. Holtmaat

• Publisher: Elsevier Science
• Year: 2002
• Topic: Biological Sciences
• eBook ISBN:
  9780080497730
• Subtopic: Neuroscience
• Index: Biological Sciences

In the past decade neuronal plasticity has become a major theme of modern neurobiology, from cellular and molecular mechanisms of synapse formation in worms and insects to behavioural recovery from strokes in elderly humans. For this reason the focus of interest in the present volume of Progress in Brain Research is on the topic of neuroplasticity in mature organisms, including humans. Contributions range from neurogenesis and synaptic plasticity in the adult primate brain, to neural mechanisms of learning and memory, and the influence of environmental factors and aging on the functional potential of the central nervous system. Several contributions focus on recent developments in neural regeneration and brain repair, providing challenging evidence that the use of stem cell neurotherapy may be beneficial to humans suffering from various neurological and psychiatric diseases. This volume integrates new information on the cellular and molecular mechanisms of neuroplasticity and highlights challenging future questions in this exciting and topical area of neuroscience.

Table of contents

• Front Cover
• PLASTICITY IN THE ADULT BRAIN: FROM GENES TO NEUROTHERAPY
• Copyright Page
• Contents
• List of Contributors
• Preface
• Acknowledgements
• Section I: Neurogenesis in adulthood: New neurons in old brains
• Section II: Brain plasticity: From molecule to neural network
• Section III: Learning and memory
• Section IV: Circadian and seasonal plasticity
• Section V: Neural plasticity in aging and neuropathology
• Section VI: Cell implantation and gene therapy
• Section VII: Stem cells: Their role in brain repair
• Subject Index