Membranes and Cell Signaling
eBook - PDF

Membranes and Cell Signaling

  1. 637 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Membranes and Cell Signaling

About this book

It should not come as too much of a surprise that biological membranes are considerably more complex than lipid bilayers. This has been made quite clear by the fluid-mosaic model which considers the cell membrane as a two-dimensional solution of a mosaic of integral membrane proteins and glycoproteins firmly embedded in a fluid lipid bilayer matrix. Such a model has several virtues, chief among which is that it allows membrane components to diffuse in the plane of the membrane and orient asymmetrically across the membrane. The model is also remarkable since it provokes the right sort of questions. Two such examples are: Does membrane fluidity influence enzyme activity? Does cholesterol regulate fluidity? However, it does not go far enough. As it turns out, there is now another version of this model, the so-called post-fluid mosaic model which incorporates two concepts, namely the existence in the membrane of discrete domains in which specific lipid-lipid, lipid-protein and protein-protein interactions occur and ordered regions that are in motion but remain separate from less ordered regions. We must admit that both are intriguing problems and of importance in guiding our thinking as to what the next model might be.We have chosen not to include the subject of membrane transport in the present volume. This obviously represents a break with convention. However, the intention is to have the topic covered subsequent volumes relating to organ systems. It would be right to regard this as an attempt to strengthen the integrated approach to the teaching of medicine.

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Yes, you can access Membranes and Cell Signaling by Edward Bittar in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Cell Biology. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Front Cover
  2. Membranes and Cell Signaling
  3. Copyright Page
  4. Contents (Volume 7B)
  5. List of Contributors
  6. Preface
  7. Chapter 14. Mechano-Sensitive Channels
  8. Chapter 15. Patch Clamping Methods and Analysis of Ion Channels
  9. Chapter 16. Functional Expression of Ionic Channels and Membrane Transporters in Xenopus Oocytes
  10. Chapter 17. The Plasma Membrane as A Transducer and Amplifier
  11. Chapter 18. G-Protein Coupled Receptors and Hormone Secretion
  12. Chapter 19. The Role of ras in Signal Transduction
  13. Chapter 20. The Polyphosphoinositide Signaling System
  14. Chapter 21. Other Lipids as Second Messengers
  15. Chapter 22. The Role of Intracellular Calcium as a Regulatory System
  16. Chapter 23. The Role of Guanylyl Cyclases as Signal Transducing Enzymes
  17. Chapter 24. Stimulus-Response Coupling in Secretory Cells
  18. Chapter 25. Cell Interactions with Extracellular Matrices
  19. Chapter 26. Intercellular Communication
  20. Index