Signal Transduction

Bastien D. Gomperts, ljsbrand M. Kramer, Peter E.R. Tatham

• Publisher: Academic Press
• Year: 2002
• eBook ISBN: 9780080541181
• Topic: Medicine
• Subtopic: Pharmacology

Signal Transduction is a well-illustrated, coherent look at cellular signaling processes. Beginning with the basics, it explains how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and then shows how these inputs are integrated and coordinated. The extensive color artwork provides the reader with a clearer comprehension of key topics, and margin notes are incorporated to highlight milestones in the evolution of signal transduction. This book serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields. - Coherent, precise text providing insight in depth to a subject that is central to cell biology and fundamental to many areas of biomedicine - Extensive conceptual colour artwork assists with the comprehension of key topics - Extensive referencing provides an invaluable link to the core and historical literature - Margin notes highlighting milestones in the evolution of our understanding of signalling mechanisms

Table of contents

• Front Cover
• Signal Transduction
• Copyright Page
• Contents
• Preface
• Chapter 1. Prologue: Signal transduction, origins and personalities
• Chapter 2. First messengers
• Chapter 3. Receptors
• Chapter 4. GTP-binding proteins and signal transduction
• Chapter 5. Effector enzymes coupled to GTP-binding proteins: Adenylyl cyclase and phospholipase C
• Chapter 6. The regulation of visual transduction
• Chapter 7. Calcium and signal transduction
• Chapter 8. Calcium signalling
• Chapter 9. Phosphorylation and dephosphorylation: Protein kinases A and C
• Chapter 10. Growth factors: Setting the framework
• Chapter 11. Signalling pathways operated by receptor protein tyrosine kinases
• Chapter 12. Signalling pathways operated by non-receptor protein tyrosine kinases
• Chapter 13. Phosphoinositide 3-kinases, protein kinase B and signalling through the insulin receptor
• Chapter 14. Signal transduction to and from adhesion molecules
• Chapter 15. Adhesion molecules and trafficking of leukocytes
• Chapter 16. Signalling through receptor bound protein serine/threonine kinases
• Chapter 17. Protein dephosphorylation and protein phosphorylation
• Chapter 18. Protein domains and signal transduction
• Index