Trends in Drug Research III
eBook - PDF

Trends in Drug Research III

  1. 272 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Trends in Drug Research III

About this book

The tradition of setting new trends in medicinal chemistry continued at the 13th Symposium where topics included chemical and biological diversity, new paradigms in drug action, and new insights in receptor mechanisms. Other topics of great interest discussed, and included in these proceedings, are the discoveries in green chemistry, the interface between organic synthesis and biosynthesis, the growing problem of resistant micro-organisms and the possibilities to identify new, and better, antibiotics. And finally, in recent developments, the discovery of small molecules with insulin sensitizing properties.

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Yes, you can access Trends in Drug Research III by H. van der Goot in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Elsevier Science
Year
2002
Print ISBN
9780444507600
eBook ISBN
9780080543239
Topic
Medicine
Subtopic
Pharmacology

Table of contents

  1. Front Cover
  2. Trends in Drug Research III
  3. Copyright Page
  4. Contents
  5. Preface
  6. Chapter 1. Towards rational design of AMPA receptor ligands: an integrated medicinal, computational, biostructural and molecular pharmacological approach
  7. Chapter 2. From heparin to synthetic antithrombotics. The pentasaccharide story and follow-up
  8. Chapter 3. A new future for synthesis?
  9. Chapter 4. Directed evolution of enantioselective enzymes as catalysts in the production of chiral pharmaceuticals
  10. Chapter 5. At the interface of organic synthesis and biosynthesis
  11. Chapter 6. What can structure tell us about function in the estrogen receptors?
  12. Chapter 7. Molecular docking and dynamics simulations in the ligand binding domain of steroid hormone receptors
  13. Chapter 8. Peroxisome proliferator-activated receptors and reverse endocrinology
  14. Chapter 9. Biomolecular mass spectrometry related to drug research
  15. Chapter 10. Chemical and biological diversity in drug discovery
  16. Chapter 11. Muscarine acetylcholine receptor knockout mice: phenotypical analysis and clinical implications
  17. Chapter 12. Changes in expression of the orphan G-protein coupled receptor GPR7 in human painful peripheral neuropathies
  18. Chapter 13. Computational methods for the analysis of molecular diversity
  19. Chapter 14. Enhancing drug discovery by acquisition of chemical diversity
  20. Chapter 15. Chemical diversity as a driving force to design and put in practice synthetic strategies leading to combinatorial libraries for lead discovery and lead optimization
  21. Chapter 16. Beyond G proteins: the role of accessory proteins in G protein-coupled receptor signalling
  22. Chapter 17. Mechanisms of action of antipsychotic drugs: the role of inverse agonism at the D2 dopamine receptor
  23. Chapter 18. Agonist channeling of α2-adrenoceptor function
  24. Chapter 19. Antibacterials as wonder drugs and how their effectiveness is being compromised
  25. Chapter 20. Pseudomonas aeruginosa quorum sensing: a target for antipathogenic drug discovery
  26. Chapter 21. Discovery and development of new anti-bacterial drugs
  27. Chapter 22. Discovery of small molecule insulin mimetics as potential novel antidiabetic agents
  28. Chapter 23. Expression databases for pharmaceutical lead optimisation
  29. Chapter 24. New developments in the pharmacology of cannabinoids
  30. Author index
  31. Subject index