Mechanisms of Memory

J. David Sweatt

• Publisher: Academic Press
• Year: 2003
• eBook ISBN:
  9780080521961
• Topic: Medicine
• Subtopic: Neurology

This book stands as the first unified overview of the cellular and molecular mechanisms underlying higher-order learning and memory. It integrates modern discoveries concerning learning and memory disorders such as mental retardation syndromes and Alzheimer's Disease, while also emphasizing the results gained from the cutting-edge research methodologies of genetic engineering, complex behavioral characterization, proteomics, and molecular biology. This book provides a foundation of experimental design that will be useful to all students pursuing an interest in laboratory research. This book is an enlightening and invaluable resource for anyone concerned with memory mechanisms.* Presents a unified view of memory mechanisms from behavior to genes and drawing examples from many different brain regions, types of learning, and various animal model systems* Includes numerous practical examples for the new investigator on how to implement research program in the area of learning and memory* Provides a balanced treatment of the strengths and weaknesses in modern experimental design

Table of contents

• Front Cover
• Mechanisms of Memory
• Copyright Page
• Contents
• Foreword
• Preface
• Acknowledgments
• Chapter 1. Introduction—The Basics of Psychological Learning and Memory Theory
• Chapter 2. Rodent Behavioral Learning and Memory Models
• Chapter 3. The Hippocampus Serves a Role in Multimodal Information Processing, and Memory Consolidation
• Chapter 4. Long-Term Potentiation as a Physiological Phenomenon
• Chapter 5. Complexities of Long-Term Potentiation
• Chapter 6. The Biochemistry of LTP Induction
• Chapter 7. Biochemical Mechanisms for Short-Term Information Storage at the Cellular Level
• Chapter 8. Biochemical Mechanisms for Long-Term Information Storage at the Cellular Level
• Chapter 9. LTP Does Not Equal Memory
• Chapter 10. Inherited Disorders of Human Memory—Mental Retardation Syndromes
• Chapter 11. Aging-Related Memory Disorders— Alzheimer’s Disease
• Chapter 12. The Chemistry of Perpetual Memory
• Index