
- 340 pages
- English
- PDF
- Available on iOS & Android
Endocrine Manifestations of Systemic Autoimmune Diseases
About this book
This book is one of the first to evaluate the role of Steroids in autoimmune rheumatic diseases from the basic mechanisms to the clinical involvements and focuses on the importance of steroidal hormones in the pathogenesis and therapeutic management of the autoimmune rheumatic diseases. In particular, the chapters analyze the mechanisms of action and the involvement of adrenal steroids (glucocorticoids) in the neuroendocrine immune system, including effects on the elderly. The perturbations of the HPA axis as a source of altered steroidal synthesis will be discussed and related to some interesting pathological conditions that commonly complicate the autoimmune rheumatic diseases such as psychosis or fibromyalgia. Concerning the role of gonadal steroids (sex hormones), several chapters will discuss clinical and epidemiological evidences of their role, as well as their effects as risk factors in autoimmune rheumatic diseases, including a section on pediatrics.- The premier issue evaluating the role of steroids in autoimmune rheumatic diseases from the basic mechanisms to the clinical involvements- Documents the latest research and indicate recent and coming new therapeutic-biological approaches to the therapy- The book will present therapeutic perspectives concerning the new glucocorticoids, and the effects of biological drugs on their synthesis
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Information
Table of contents
- Cover
- Table of contents
- Preface
- Chapter 1. Introduction
- Chapter 2. Elementary Descriptive Statistical Techniques
- Chapter 3. Probability Theory
- Chapter 4. Random Variables and Probability Distributions
- Chapter 5. Bivariate Probability Distributions
- Chapter 6. Discrete Parametric Probability Distributions
- Chapter 7. Continuous Parametric Probability Distributions
- Chapter 8. Sampling and the Sampling Distribution of a Statistic
- Chapter 9. The Chi-Square, Studentās t, and Snedecorās F Distributions
- Chapter 10. Point Estimation and Properties of Point Estimators
- Chapter 11. Interval Estimation and Confidence Interval Estimates
- Chapter 12. Tests of Parametric Statistical Hypotheses
- Chapter 13. Nonparametric Statistical Techniques
- Chapter 14. Testing Goodness of Fit
- Chapter 15. Testing Goodness of Fit: Contingency Tables
- Chapter 16. Bivariate Linear Regression and Correlation
- Appendix A
- Solutions to Selected Exercises
- References and Suggested Reading
- Index