- 982 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
The Practice of Medicinal Chemistry
About this book
The Practice of Medicinal Chemistry fills a gap in the list of available medicinal chemistry literature. It is a single-volume source on the practical aspects of medicinal chemistry. Considered ""the Bible"" by medicinal chemists, the book emphasizes the methods that chemists use to conduct their research and design new drug entities. It serves as a practical handbook about the drug discovery process, from conception of the molecules to drug production. The first part of the book covers the background of the subject matter, which includes the definition and history of medicinal chemistry, the measurement of biological activities, and the main phases of drug activity. The second part of the book presents the road to discovering a new lead compound and creating a working hypothesis. The main parts of the book discuss the optimization of the lead compound in terms of potency, selectivity, and safety. The Practice of Medicinal Chemistry can be considered a ""first-read"" or ""bedside book"" for readers who are embarking on a career in medicinal chemistry.NEW TO THIS EDITION: * Focus on chemoinformatics and drug discovery * Enhanced pedagogical features* New chapters including: - Drug absorption and transport - Multi-target drugs* Updates on hot new areas: NEW! Drug discovery and the latest techniques NEW! How potential drugs can move through the drug discovery/ development phases more quickly NEW! Chemoinformatics
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Yes, you can access The Practice of Medicinal Chemistry by Camille Georges Wermuth in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Front Cover
- The Practice of Medicinal Chemistry
- Copyright Page
- Contents
- Biography
- Section Editors
- Contributors
- Preface to the First Edition
- Preface to the Second Edition
- Preface to the Third Edition
- Part I: General Aspects of Medicinal Chemistry
- Part II: Lead Compound Discovery Strategies
- Part III: Primary Exploration of StructureâActivity Relationships
- Part IV: Substituents and Functions: Qualitative and Quantitative Aspects of StructureâActivity Relationships
- Part V: Spatial Organization, Receptor Mapping and Molecular Modeling
- Part VI: Chemical Modifications Influencing the Pharmacokinetic Properties
- Part VII: Pharmaceutical and Chemical Means to Solubility and Formulation Problems
- Part VIII: Development of New Drugs: Legal and Economic Aspects
- Index