HPLC Method Development for Pharmaceuticals
eBook - PDF

HPLC Method Development for Pharmaceuticals

  1. 532 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

HPLC Method Development for Pharmaceuticals

About this book

High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective.HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge.- Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory- Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities)- Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase

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Yes, you can access HPLC Method Development for Pharmaceuticals by Satinder Ahuja,Henrik Rasmussen in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2011
eBook ISBN
9780080554198
Topic
Medicine
Subtopic
Pharmacology

Table of contents

  1. Front Cover
  2. HPLC METHOD DEVELOPMENT FOR PHARMACEUTICALS
  3. Copyright Page
  4. CONTENTS
  5. PREFACE
  6. CONTRIBUTORS
  7. Chapter 1. Overview of HPLC Method Development for Pharmaceuticals
  8. Chapter 2. HPLC Theory
  9. Chapter 3. HPLC Columns and Packings
  10. Chapter 4. Column Characterization and Selection
  11. Chapter 5. Chiral Separations
  12. Chapter 6. Contemporary Liquid Chromatographic Systems for Method Development
  13. Chapter 7. Hyphenated Techniques
  14. Chapter 8. HPLC Sample Preparation
  15. Chapter 9. Instrument Qualification and Software Validation
  16. Chapter 10. Pharmaceutical Development: From Pre-Clinical to Post Approval
  17. Chapter 11 . HPLC Method Development for Drug Discovery LC-MSAssays in Rapid PK Applications
  18. Chapter 12. HPLC Method Development in Early Phase Pharmaceutical Development
  19. Chapter 13. HPLC Method Development in Late Phase Pharmaceutical Development
  20. Chapter 14. Use of HPLC for In-process Testing
  21. Chapter 15. Method Development for Biomolecules
  22. Chapter 16. Method Validation
  23. Chapter 17. Troubleshooting in High Performance Liquid Chromatography
  24. Chapter 18. Molecularly Imprinted Polymers as Sorbents for Separations and Extractions
  25. Index