eBook - PDF

Metabolic Basis of Detoxication

Name: Metabolic Basis of Detoxication
ISBN: 9780323137997

Metabolism of Functional Groups

William B. Jakoby,

375 pages
English
PDF
Available on iOS & Android

eBook - PDF

Metabolic Basis of Detoxication

Metabolism of Functional Groups

William B. Jakoby,

About this book

Metabolic Basis of Detoxication: Metabolism of Functional Groups considers the possible fates of the relatively circumscribed number of functional groups that xenobiotics bear. An understanding of the possible reactions, and the chemical and biological factors influencing them, will contribute to the overall predictability of the fate of "real" molecules. This approach attempts to knit together the understanding of metabolic pathways with that of the enzymes that catalyze the specific steps. The book contains 18 chapters and begins with a discussion of the biological oxidation of carbon atoms. This is followed by separate chapters on the metabolism of halogenated aliphatic hydrocarbons, aryl halides, heterocyclic rings, alcohols, aldehydes, and ketones. Subsequent chapters cover oxidative processes such as metabolic dealkylations and biological oxidation at nitrogen centers; the reduction of nitro and azo compounds and tertiary amine N-oxides; the oxidation, alkylation, acylation, and glycosylation of mercaptans; epoxide metabolism; and conjugation of phenols. The book aims to inform and interest the pharmacologist and toxicologist concerning the biochemical aspects and to orient the biochemist to the pharmacological insights required in dealing with the metabolism of xenobiotics.

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Yes, you can access Metabolic Basis of Detoxication by William B. Jakoby in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Zoology. We have over one million books available in our catalogue for you to explore.