Neural Models of Plasticity

Experimental and Theoretical Approaches

John H. Byrne

• Publisher: Academic Press
• Year: 2012
• Print ISBN: 9780121489557
• eBook ISBN: 9780323149839
• Topic: Psychology
• Subtopic: Cognitive Psychology & Cognition
• Index: Psychology

Neural Models of Plasticity: Experimental and Theoretical Approaches focuses on the use of theoretical and empirical methods in investigating the role of neuronal plasticity in learning, memory, and complex brain functions. It examines the neuromodulation in relation to associative learning and memory, developmental assembly of various components of learning and memory, cellular and molecular processes contributing to associative and non-associative learning, and higher-order features of classical conditioning. Organized into 19 chapters, this volume begins with an overview of the central pathways mediating conditioning in the marine mollusk Hermissenda and the behavior modified by conditioning, along with the role of neuromodulation in associative learning in this organism. It then proceeds with a discussion of learning and memory in the marine mollusk Aplysia, the Hebb rule for synaptic plasticity, a drive-reinforcement model of neuronal function for predicting classical conditioning phenomena, and the relationship between olfactory processing and associative memory. The reader is also introduced to a neural circuit for classical conditioning of the eyelid closure response, molecular mechanisms and roles of long-term depression in cerebellar function, and functions of neuronal networks in the hippocampus and neocortex in memory. The book concludes with a chapter on models of calcium regulation in neurons. This book is a valuable resource for neurobiologists, psychologists, adaptive systems theorists, and others working in the fields of anatomy, physiology, neurophysiology, molecular biophysics, chemistry, biology, and psychiatry.

Table of contents

• Front Cover
• Neural Models of Plasticity: Experimental and Theoretical Approaches
• Copyright Page
• Table of Contents
• Contributors
• Preface
• Chapter 1. Associative Learning, Memory, and Neuromodulation in Hermissenda
• Chapter 2. Developmental Assembly of Multiple Components of Learning and Memory in Aplysia
• Chapter 3. Turtles All the Way Down: Some Molecular Mechanisms Underlying Long-Term Sensitization in Aplysia
• Chapter 4. Mathematical Model of Cellular and Molecular Processes Contributing to Associative and Nonassociative Learning in Aplysia
• Chapter 5. A Simple Circuit Model for Higher-Order Features of Classical Conditioning
• Chapter 6. The Hebb Rule for Synaptic Plasticity: Algorithms and Implementations
• Chapter 7. Classical Conditioning Phenomena Predicted by a Drive- Reinforcement Model of Neuronal Function
• Chapter 8. Olfactory Processing and Associative Memory: Cellular and Modeling Studies
• Chapter 9. Neural Circuit for Classical Conditioning of the Eyelid Closure Response
• Chapter 10. Long-Term Depression: Possible Cellular Mechanism for Learning Mediated by the Cerebellum
• Chapter 11. Simulation of a Classically Conditioned Response: A Cerebellar Neural Network Implementation of the Sutton–Barto–Desmond Model
• Chapter 12. Memory and the Hippocampus
• Chapter 13. Functions of Neuronal Networks in the Hippocampus and Neocortex in Memory
• Chapter 14. Long-Term Potentiation in Two Synaptic Systems of the Hippocampal Brain Slice
• Chapter 15. The Role of Norepinephrine in Long-Term Potentiation at Mossy-Fiber Synapses in the Hippocampus
• Chapter 16. Some Possible Functions of Simple Cortical Networks Suggested by Computer Modeling
• Chapter 17. Neural Architecture and Biophysics for Sequence Recognition
• Chapter 18. Local Synaptic and Electrical Interactions in Hippocampus: Experimental Data and Computer Simulations
• Chapter 19. Models of Calcium Regulation in Neurons
• Index