Antibody Production in Man

In Vitro Synthesis and Clinical Implications

Anthony S. Fauci

• Publisher: Academic Press
• Year: 2012
• Print ISBN:
  9780122499500
• eBook ISBN:
  9780323151528
• Topic: Medicine
• Subtopic: Clinical Medicine

Antibody Production in Man: In Vitro Synthesis and Clinical Implications is composed of the proceedings of the Catharijne Conference on immunology held in Utrecht, Holland on March 15-18, 1978. The conference focuses on the in vitro induction and regulation of immunoglobulin and antibody synthesis by human lymphocytes. It aims to present, analyze, exchange, and criticize data among the different investigators and to attempt to resolve apparent inconsistencies and contradictions. The book first discusses the mitogen- and antigen-induced B-cell activation. It then explains the subpopulations of lymphocytes involved in the regulation of in vitro B-cell function and the clinical implications in the study of in vitro B-cell function. This book reflects the stimulation as well as the frustration during the workshop. It will serve as a small force and focus of direction in this most interesting, complex, and relevant area of human immunobiology.

Table of contents

• Front Cover
• Antibody Production in Man: In Vitro Synthesis and Clinical Implications
• Copyright Page
• Table of Contents
• CONTRIBUTORS
• PREFACE
• CHAPTER 1. CONSIDERATION OF ANTIBODY DEFICIENCY DISEASES IN RELATION TO NORMAL B-CELL DEVELOPMENT
• CHAPTER 2. POKEWEED MITOGEN-INDUCED PFC RESPONSES OF HUMAN PERIPHERAL BLOOD LYMPHOCYTES: REGULATION OF B-CELL TRIGGERING
• CHAPTER 3. INDUCTION OF ANTIBODY SYNTHESIS IN HUMAN LYMPHOCYTES FROM DIFFERENT ORGANS BY DIFFERENT PBA SUBSTANCES
• CHAPTER 4. THE PLAQUE-FORMING CELL RESPONSE OF HUMAN BLOOD LYMPHOCYTES COCULTIVATION OF LYMPHOCYTES FROM DIFFERENT INDIVIDUALS
• PART I: GENERAL DISCUSSION MITOGEN INDUCED B CELL ACTIVATION. I.
• PART II: GENERAL DISCUSSION MITOGEN-INDUCED B-CELL ACTIVATION. II.
• PART III: GENERAL DISCUSSION ANTIGEN INDUCED B CELL ACTIVATION. I.
• PART IV: GENERAL DISCUSSION ANTIGEN INDUCED B CELL ACTIVATION. II.
• PART V: GENERAL DISCUSSION SUBPOPULATIONS OF LYMPHOCYTES INVOLVED IN THE IN VITRO REGULATION OF B CELL FUNCTION. I.
• PART VI: GENERAL DISCUSSION SUBPOPULATIONS OF LYMPHOCYTES INVOLVED IN THE IN VITRO REGULATION OF B CELL-FUNCTION. II.
• PART VII: GENERAL DISCUSSION CLINICAL IMPLICATIONS IN THE STUDY OF IN VITRO B CELL FUNCTION. I.
• PART VIII: GENERAL DISCUSSION CLINICAL IMPLICATIONS IN THE STUDY OF IN VITRO B CELL FUNCTION. II.
• SUMMARY OF WORKSHOP: HUMAN B CELL FUNCTION: RECENT ADVANCES, UNANSWERED QUESTIONS, AND FUTURE DIRECTIONS
• INDEX