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Extracellular Matrix
About this book
Extracellular Matrix contains the proceedings of the symposium ""The Extracellular Matrix,"" sponsored by the Michigan Molecular Institute and held in Midland, Michigan, on June 28-July 2, 1982. The papers explore the role played by the extracellular matrix (ECM) in the physiology of a cell, particularly in the regulation of cellular phenotypes, differentiation, and proliferation. The progress made in isolating and defining the chemistry and functional interactions of the ECM components is discussed, along with the biology of the ECM. This book is comprised of 52 chapters and begins with an introduction to the ECM, with emphasis on the question of whether the malignant process can be defined in a cell culture model, and in particular, whether the pericellular matrix is characteristically altered in cancer. The discussion then turns to the structure of the heparan sulfate proteoglycans and the molecular mechanisms responsible for the association of these molecules with the surfaces of cultured cells. Subsequent chapters focus on the chemistry of ECM components such as collagen, glycosaminoglycans, and adhesive glycoproteins, along with their functional interactions, biosynthesis, turnover, and degradation. The final section is devoted to the diseased states of ECM. This monograph should serve as a valuable reference for biochemists as well as undergraduate and graduate students of biochemistry.
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Yes, you can access Extracellular Matrix by Susan Hawkes in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Zoology. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Front Cover
- Extracellular Matrix
- Copyright Page
- Table of Contents
- PARTICIPANTS
- PREFACE
- INTRODUCTION
- SECTION I: CHEMISTRY OF ECM COMPONENTS: COLLAGENS, GLYCOSAMINOGLYCANS, AND ADHESIVE GLYCOPROTEINS
- SECTION II: SYSTEMS FOR STUDYING THE ROLE OF ECM IN GROWTH AND DIFFERENTIATION
- SECTION III: CELL-SUBSTRATUM ADHESION AND ADHESION-DEFICIENT CELL LINES
- SECTION IV: BIOLOGICAL EFFECTS OF THE ECM IN TISSUE INTERACTIONS AND DIFFERENTIATION
- SECTION V: FUNCTIONAL INTERACTIONS OF ECM COMPONENTS
- SECTION VI: GROWTH OF CELLS ON SURFACES DERIVATIZED WITH ECM COMPONENTS
- SECTION VII: STRUCTURAL AND FUNCTIONAL STUDIES OF THE COMPONENTS OF THE ECM
- SECTION VIII: MODULATION OF MAMMARY CELL PHENOTYPES BY THE ECM
- SECTION IX: BIOSYNTHESIS, TURNOVER, AND DEGRADATION OF ECM COMPONENTS
- SECTION Χ: DISEASED STATES OF ECM
- INDEX