Immune Regulators In Transfer Factor

Amanullah Khan, Amanullah Khan

• Publisher: Academic Press
• Year: 2012
• ISBN:
  9780323142540
• Topic: Medicine
• Subtopic: Immunology

Immune Regulators in Transfer Factor is a collection of papers presented at the Third International Symposium on Transfer Factor held on October 12-14, 1978 at the Wadley Institutes of Molecular Medicine in Dallas, Texas. Contributors focus on immune regulators occurring in transfer factor, a dialyzable component of leukocyte lysates. The isolation and characterization of the immunologically active molecules, as well as tests for in vitro and in vivo, are described. This volume is organized into five sections encompassing 73 chapters and begins with an overview of animal models used in research on dialyzable leukocyte extracts, their modulation of suppressor activity, effects in mice, and activity and specificity of human and bovine transfer factor. The next section considers in vitro testing, touching on topics such as the quantification and biological assays of transfer factor; the specificity of transfer factor action on macrophage migration; and the effect of transfer factor therapy on antibody-dependent cytotoxic activity in humans. The reader is then introduced to the preparation, purification, and characterization of transfer factor, as well as clinical investigations ranging from phase I studies to randomized controlled trials. This book will be of interest to scientists and researchers in fields such as molecular medicine, biomedicine, microbiology, immunology, oncology, pathology, and immunotherapy.