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The Isoquinoline Alkaloids Chemistry and Pharmacology
The Isoquinoline Alkaloids Chemistry and Pharmacology

The Isoquinoline Alkaloids Chemistry and Pharmacology

Maurice Shamma
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614 pages
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English
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The Isoquinoline Alkaloids Chemistry and Pharmacology

Maurice Shamma
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About This Book

The Isoquinoline Alkaloids: Chemistry and Pharmacology presents an overview of the chemistry, biogenesis, spectroscopy, and pharmacology of the isoquinoline alkaloids. This book examines the significant and interesting aspects of alkaloids.
Organized into 32 chapters, this book starts with a discussion of the biogenesis of the isoquinolines and the various pharmacological effects of simple tetrahydroisoquinolines that have stimulant and convulsive properties. This text then explores the infrared absorptions, with emphasis on wavelength and frequency. Other chapters include topics on synthesis, degradation, reactions, absolute configuration, as well as on ultraviolet and nuclear magnetic resonance spectroscopy. This book further explores the various methods available for the preparation of simple tetrahydroisoquinolines, including the Bischler–Napieralski, Pictet–Spengler, and phenolic cyclization, as well as the Friedel–Crafts acylation. The last chapter deals with ancistrocladine, which is the first isoquinoline alkaloid found to possess a methyl group.
Biochemists and biophysicists will find this book useful.

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Information

Publisher
Elsevier Science
Year
2012
ISBN
9780323144506
Topic
Physical Sciences
Subtopic
Organic Chemistry

Table of contents