molecular Approaches to Immunology

E.E. Smith

• Publisher: Academic Press
• Year: 2012
• Print ISBN:
  9780126510508
• eBook ISBN:
  9780323153966
• Topic: Biological Sciences
• Subtopic: Biology
• Index: Biological Sciences

Molecular Approaches to Immunology is the 9th volume of the series ""Miami Winter Symposia"". This volume presents papers that cover various aspects about cellular and modern immunology. Cellular immunology deals with the interactions of cells and molecules of the immune system and how these interactions help eliminate pathogens. The main goal of this book is to discuss and provide basic assumptions, approaches, and direction about the advances in the research of immunological science. In relation to this, the chapters of the book examine the recognition of antigen by T-lymphocytes, the role of cell interactions in determining the immune responsiveness, and the concepts behind clonal selection. The book also explains the different genes coding used for antibodies and the characterization of cell surface receptors at molecular level. Furthermore, it examines the evidences for genetic restrictions in cell interactions and the chemical properties of thymosin used in physiological studies. Discussions on the immunoregulation and immunological tolerance by T cells and the growth control of mammalian cells are also presented in this volume. This compilation will be invaluable to biologists, medical practitioners, professors, and students.

Table of contents

• Front Cover
• Molecular Approaches to Immunology
• Copyright Page
• Table of Contents
• SPEAKERS, CHAIRMEN, AND DISCUSSANTS
• PREFACE
• The Sixth Feodor Lynen Lecture
• CHAPTER 1. THE SHOCK OF MOLECULAR RECOGNITION
• Chapter 2. THE SUBJECT AND STYLE OF MODERN IMMUNOLOGY: AN INTRODUCTION
• Chapter 3. CURRENT CONCEPTS IN CELLULAR IMMUNOLOGY
• Chapter 4. RECOGNITION OF ANTIGEN BY T LYMPHOCYTES
• Chapter 5.THE LOGIC OF CELL INTERACTIONS IN DETERMINING IMMUNE RESPONSIVENESS
• Chapter 6.THE USE OF MUTANT MYELOMA CELLS TO EXPLORE THE PRODUCTION OF IMMUNOGLOBULINS
• Chapter 7.IMMUNOGLOBULIN GENES IN A MOUSE MYELOMA AND IN MUTANT CLONES
• Chapter 8. GENES CODING FOR ANTIBODIES
• Chapter 9. THE ORGANIZATION AND DIVERSITY OF IMMUNOGLOBULIN κ AND λ GENES
• Chapter 10. CELL SURFACE ANTIGENS AND CELL SURFACE PROTEINS
• Chapter 11.THE ROLE OF PRODUCTS OF THE HISTOCOMPATIBILITY GENE COMPLEX IN IMMUNE RESPONSES
• Chapter 12.THE ROLE OF THYMOSIN AND THE ENDOCRINE THYMUS ON THE ONTOGENESIS AND FUNCTION OF T - CELLS
• Chapter 13. IMMUNOREGULATION BY T CELLS
• Chapter 14. CONTROL OF GROWTH OF MAMMALIAN CELLS
• Chapter 15. RESTRICTED CLONAL RESPONSES: A TOOL IN UNDERSTANDING ANTIBODY SPECIFICITY
• Chapter 16. REPETITIVE HINGE REGION EQUENCES IN A γ3 HEAVY CHAIN DISEASE PROTEIN-ISOLATION OF AN 11,000 DALTON FRAGMENT
• Chapter 17. STRUCTURAL CHARACTERIZATION OF A MUTANT HUMAN LAMBDA TYPE L-CHAIN IMMUNOGLOBULIN
• Chapter 18. HETEROGENEITY OF THE C-REGION OF AN IgGl IMMUNOGLOBULIN: THE STRUCTURE OF γ-HEAVY CHAIN DISEASE PROTEIN BAZ
• Chapter 19. GROWTH FACTOR FOR A VIRAL TRANSFORMED CELL FROM RAT LIVER AND HEMICORPUS PERFUSIONS
• Chapter 20. LYMPHOCYTE RESPONSES TO MITOGENS AND ANTIGENS IN AGAROSE-GEL CULTURES
• Chapter 21. STEROL SYNTHESIS IN NORMAL, PHYTOHEMAGGLUTININ-STIMULATED, AND LEUKEMIC MOUSE LYMPHOCYTES
• Chapter 22. CAN PROTEIN SYNTHESIS IN CULTURED CELLS BE REGULATED BY MEMBRANE-MEDIATED EVENTS
• Chapter 23. ALTERATION OF MEMBRANE ANTIGENS BY TRYPSIN
• Chapter 24. IgM Complex Receptors on T and B Lymphocytes
• Chapter 25.B AND T LYMPHOCYTES IN DYSGAMMAGLOBULINEMIA
• Chapter 26. THE ROLE OF THYMIC EXTRACT IN TRANSFER OF DELAYED HYPERSENSITIVITY (D.H.S.) AND IMMUNOSTIMULATION
• Chapter 27. GROWTH PROPERTIES AND ALLOANTIGENIC EXPRESSION OF MURINE LYMPHOBLASTIC CELL LINES GROWN IN SUSPENSION CULTURE
• Chapter 28. REGUIATION OF Ab ACTIVITY OF KABBIT (Rab) Ig LYMPHOCYTES (LC) BY PRODUCTS OF Rab Ig~LC.
• Chapter 29. EVIDENCE FOR THE GENETIC CONTROL OF ANTIGENIC MODULATION
• Chapter 30. THE RESPONSE OF CONGENITALLY ATHYMIC (NUDE) MICE TO INFECTION WITH MYCOBACTERIUM BOVIS (STRAIN BCG
• Chapter 31. NONSPECIFIC STIMULATORS OF THEÎ IMMUNE SYSTEM