Trial Designs and Outcomes in Dementia Therapeutic Research
eBook - PDF

Trial Designs and Outcomes in Dementia Therapeutic Research

  1. 324 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Trial Designs and Outcomes in Dementia Therapeutic Research

About this book

Given the increased attention of clinicians, researchers, and the pharmaceutical industry to the management and treatment of dementia not only in the elderly but also in increasingly younger populations, the demands for effective evidence-based pharmaceutical control of dementia and quantitative assessment of outcomes have increased. From the first steps in the early 1960s to the controversial landmark paper of Summers and colleagues to the most recent trials, it is clear both that much progress has been made and that much remains to be done. This book is written to take stock of what is now usefully known and to speculate on directions for the future.

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Yes, you can access Trial Designs and Outcomes in Dementia Therapeutic Research by Kenneth Rockwood,Serge Gauthier in PDF and/or ePUB format, as well as other popular books in Medicine & Geriatrics. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2005
Print ISBN
9781841843216
eBook ISBN
9780203340653
Edition
1
Topic
Medicine
Subtopic
Geriatrics

Table of contents

  1. Cover
  2. Half Title
  3. Title Page
  4. Copyright Page
  5. Table of Contents
  6. List of Contributors
  7. Preface
  8. 1: Introduction: Expectations of Treatment with the Cholinesterase Inhibition Strategy
  9. 2: The History of Therapeutic Trials in Dementia
  10. 3: Treatment Hypotheses
  11. 4: Clinical Trial Designs and Endpoint Selection
  12. 5: The Use of Qualitative Research
  13. 6: Inclusion and Exclusion Criteria
  14. 7: Global Assessment Measures
  15. 8: Cognitive Outcomes
  16. 9: Functional Outcomes
  17. 10: Behavioural Outcomes
  18. 11: Quality of Life Outcomes
  19. 12: Caregiver Burden Outcomes
  20. 13: Structural Neuroimaging Outcomes
  21. 14: Guidelines for Randomised Clinical Studies in Parkinsonā€™s Disease with Dementia and Dementia with Lewy Bodies
  22. 15: Clinical Trials for Vascular Cognitive Impairment
  23. 16: Clinical Trials for Primary Prevention in Dementia
  24. 17: Clinical Trials for Memantine
  25. 18: Clinical Trials for Psychotropic Agents in Alzheimerā€™s Disease
  26. 19: Clinical Trials for Psychosocial Interventions Aimed at Caregivers of People with Dementia
  27. 20: Pharmacoeconomic Outcomes
  28. 21: Executive Dysfunction in Dementia
  29. 22: Ethical Considerations in the Conduct of Clinical Trials for Alzheimerā€™s Disease
  30. 23: Designs for Trials when there is a Standard Therapy: Superiority, Equivalence, Non-Inferiority
  31. 24: Conclusion: Lessons from Clinical Trials in Dementia
  32. Index