Adverse Reactions to Drugs

O. L. Wade, Linda Beeley

• Publisher: Butterworth-Heinemann
• Year: 2013
• Print ISBN:
  9780433345510
• eBook ISBN:
  9781483141770
• Edition: 2
• Topic: Medicine
• Subtopic: Pharmacology

Adverse Reactions to Drugs, Second Edition focuses on the problems posed by the adverse responses to drugs, as well as drug interactions, dosage, and drug metabolism. The publication first tackles adverse reactions and factors which predispose to adverse drug reactions. Topics include dose adjustment, overdose, renal failure, cumulation, side effects, drug allergy, cumulative overdose, and delayed effects. The text then ponders on drug interactions, including renal excretion, drug metabolism, mutual toxicity, and interactions affecting transport to site of action. The manuscript examines adverse reactions in dental practice, drugs used in pregnancy, the neonate, and lactation, and problems for the pharmaceutical industry before marketing a new drug. Discussions focus on ethical problems of drug studies in man, pregnancy, hemorrhage, oxygen toxicity, chloramphenicol, drugs and lactation, drugs used in dental practice, and local anesthetics. The book then elaborates on monitoring adverse reactions to drugs and the therapeutic audit and drug regulatory bodies and their problems. The publication is a valuable source of data for doctors and dentists wanting to focus on research on the adverse reaction to drugs.

Table of contents

• Front Cover
• Adverse Reactions to Drugs
• Copyright Page
• Table of Contents
• PREFACE TO THE SECOND EDITION
• ACKNOWLEDGMENTS
• CHAPTER I. THE DAWN OF CONCERN
• CHAPTER II. ADVERSE REACTIONS
• CHAPTER III. IFACTORS WHICH PREDISPOSE TO ADVERSE DRUG REACTIONS
• CHAPTER IV. DRUG INTERACTIONS
• CHAPTER V. ADVERSE REACTIONS IN DENTAL PRACTICE
• CHAPTER VI. DRUGS USED IN PREGNANCY,THE NEONATE AND LACTATION
• CHAPTER VII. PROBLEMS FOR THE PHARMACEUTICAL INDUSTRY BEFORE MARKETING A NEW DRUG
• CHAPTER VIII. MONITORING ADVERSE REACTIONS TODRUGS AND THE THERAPEUTIC AUDIT
• CHAPTER IX. DRUG REGULATORY BODIES AND THEIR PROBLEMS
• CHAPTER X. THE FUTURE
• APPENDIX I: ADVERSE REACTIONS TO DRUGS
• APPENDIX II: DRUG INDUCED DISEASE
• APPENDIX III: DRUG INTERACTION TABLES
• APPENDIX IV: DRUGS IN PREGNANCY
• REFERENCES
• INDEX
• DRUG INDEX