Biology of Proteoglycans
  1. 415 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

About this book

Biology of Proteoglycans provides a representative, but by no means inclusive, sample of current research on the role of proteoglycans in the cell biology of the extracellular matrix. The book is organized into four areas: methodological developments; proteoglycan metabolism; proteoglycans in cartilage; and proteoglycans in "soft" tissues. It begins with discussions of current methodological developments which have had enormous impact on understanding the complexity of proteoglycan structure. These include the use of monoclonal antibodies to probe the structure of the protein and carbohydrate portions of proteoglycans; and studies on the genes that code for the proteoglycan protein cores and associated proteins. This is followed by separate chapters on various aspects of proteoglycan metabolism, including the synthetic pathway used by cells to synthesize proteoglycans containing heparin and heparan sulfate; the molecular organization of different proteoglycans in cartilage; the role of proteoglycans and associated proteins in the calcification process in growth plate; and the emerging field of proteoglycans in "soft" or noncartilagenous tissue.

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Information

Year
2013
Print ISBN
9780127506500
eBook ISBN
9781483259406

Table of contents

  1. Front Cover
  2. Biology of Proteoglycans
  3. Copyright Page
  4. Table of Contents
  5. Preface
  6. CHAPTER 1. MONOCLONAL ANTIBODIES AS PROBES FOR ELUCIDATING PROTEOGLYCAN STRUCTURE AND FUNCTION
  7. CHAPTER 2. MOLECULAR BIOLOGY OF PROTEOGLYCANS AND LINK PROTEINS
  8. CHAPTER 3. BIOSYNTHESIS OF HEPARIN AND HEPARAN SULFATE
  9. CHAPTER 4. PROTEOGLYCAN METABOLISM BY RAT OVARIAN GRANULOSA CELLS IN VITRO
  10. CHAPTER 5. INTEGRAL MEMBRANE PROTEOGLYCANS AS MATRIX RECEPTORS: ROLE IN CYTOSKELETON AND MATRIX ASSEMBLY AT THE EPITHELIAL CELL SURFACE
  11. CHAPTER 6. STRUCTURAL ORGANIZATION OF PROTEOGLYCANS IN CARTILAGE
  12. CHAPTER 7. PROTEOGLYCANS, CHONDROCALCIN, AND THE CALCIFICATION OF CARTILAGE MATRIX IN ENDOCHONDRIAL OSSIFICATION
  13. CHAPTER 8. BIOCHEMICAL BASIS OF AGE-RELATED CHANGES IN PROTEOGLYCANS
  14. CHAPTER 9. EXTRACELLULAR MATRIX COMPONENTS OF THE SYNAPSE
  15. CHAPTER 10. BLOOD VESSEL PROTEOGLYCANS
  16. CHAPTER 11. HEPARAN SULFATE SPECIES AND BLOOD VESSEL WALL FUNCTION
  17. CHAPTER 12. CELL-ASSOCIATED PROTEOGLYCANS IN HUMAN MALIGNANT MELANOMA
  18. CHAPTER 13. INTRACELLULAR PROTEOGLYCANS IN CELLS OF THE IMMUNE SYSTEM
  19. INDEX

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Yes, you can access Biology of Proteoglycans by Thomas N. Wight, Robert P. Mecham, Thomas N. Wight,Robert P. Mecham in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Zoology. We have over 1.5 million books available in our catalogue for you to explore.