- 769 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
About this book
Cephalosporins and Penicillins: Chemistry and Biology describes the studies made on cephalosporin in relation to the scientific and medicinal benefits that can be derived from cephalosporin C. This collection discusses how cephalosporin C is produced through modern isolation methods. One paper discusses its structure through chemical means, its degradation products, its derivative and other metabolic products such as penicillin N and cephalosporin P. Another paper explains the preparation method for 7-aminocephalosporanic acid and 6-aminopenicillanic acid through biological or chemical means. Another paper explains the alteration of the dihydrothiazine ring of the cephalosporins as the functionalities of these rings are chemically difficult to obtain. One paper also explains the rearrangements of cephalosporins and penicillins; cephalosporin can be synthesized from penicillin through an intermediacy of penicillin sulfoxide. Other papers discuss the pharmacology and toxicology of cephalosporins, as well as the practical tests and methods of assay that can be used in most cephalosporins, and in some cases, in penicillins. This book can prove useful for pharmacologists, microchemists, research workers, and technologists dealing with toxicology.
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Table of contents
- Front Cover
- Cephalosporins and Penicillins: Chemistry and Biology
- Copyright Page
- Table of Contents
- LIST OF CONTRIBUTORS
- PREFACE
- Chapter 1. Cephalosporin C
- Chapter 2. Preparative Methods for 7-Aminocephalosporanic Acid and 6-Aminopenicillanic Acid
- Chapter 3. Modifications of the β-Lactam System
- Chapter 4. Alteration of the Dihydrothiazine Ring Moiety
- Chapter 5. Rearrangements of Cephalosporins and Penicillins
- Chapter 6. Total Syntheses of Penicillins and Cephalosporins
- Chapter 7. Chemical and Biological Activity: Inferences from X-Ray Crystal Structures
- Chapter 8. Physical-Chemical Properties of Cephalosporins and Penicillins
- Chapter 9. Microbial Synthesis of Cephalosporin and Penicillin Compounds
- Chapter 10. Biological Reactions of Cephalosporins and Penicillins
- Chapter 11. Biological Evaluation
- Chapter 12. Structure-Activity Relationships of β-Lactam Antibiotics
- Chapter 13. Pharmacology and Toxicology of Cephalosporins
- Chapter 14. Analytical Procedures for Cephalosporins
- Chapter 15. β-Lactam Antibiotics from Streptomyces
- Chapter 16. Appendix
- AUTHOR INDEX
- SUBJECT INDEX
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Yes, you can access Cephalosporins and Penicillins by Edwin H. Flynn in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Chemistry. We have over 1.5 million books available in our catalogue for you to explore.