Male Reproductive Toxicology
eBook - PDF

Male Reproductive Toxicology

  1. 402 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Male Reproductive Toxicology

About this book

Methods in Toxicology, Volume 3: Male Reproductive Toxicology, Part A, deals with the male reproductive system and discusses methods that will help identify toxicant-induced changes at all levels in living organisms. It is important to realize that a toxic effect does not occur in a vacuum. All work in toxicology must be predicated on a demonstrated adverse effect in vivo. If good toxicology cannot exist in a vacuum, then there must be a structure. Thus, the book begins by presenting a few models as examples of the ways experiments could be grouped to define the toxicity of a chemical. This is followed by separate chapters on methods such as male mouse sexual behavior test; in vitro techniques for assessing pituitary secretory function; histological methods for preservation of the rat testis; procedures for assessing testicular sperm head counts in mice, rats, and dogs; and guidelines for conducting rodent dominant lethal tests. Subsequent chapters cover topics such as methods for the isolation and purification of Leydig cells from rat and mouse testes, and techniques used in semen analysis and fertility assessment in the rabbit.

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Yes, you can access Male Reproductive Toxicology by Robert E. Chapin, Jerrold J. Heindel, Robert E. Chapin,Jerrold J. Heindel in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Academic Press
Year
2013
Print ISBN
9780124612075
eBook ISBN
9781483270951
Topic
Medicine
Subtopic
Pharmacology

Table of contents

  1. Front Cover
  2. Male Reproductive Toxicology, Part A
  3. Copyright Page
  4. Table of Contents
  5. Contributors
  6. Chapter 1. Introduction
  7. Chapter 2. Male Mouse Sexual Behavior Test
  8. Chapter 3. In Vitro Techniques for Assessing Pituitary Secretory Function
  9. Chapter 4. Histological Methods for Evaluation of the Testis
  10. Chapter 5. Application of Testicular Sperm Head Counts in the Assessment of Male Reproductive Toxicity
  11. Chapter 6. Stage Synchronization in Rat Seminiferous Tubules Using Vitamin A Depletion and Repletion
  12. Chapter 7. Spermatogonial Stem Cells: Assessing Their Survival and Ability to Produce Differentiated Cells
  13. Chapter 8. Dominant Lethal Tests in Male and Female Mice
  14. Chapter 9. Transillumination–Phase-Contrast Microscopic Techniques for Evaluation of Male Germ Cell Toxicity and Mutagenicity
  15. Chapter 10. Isolation and Culture of Leydig Cells from Adult Rats
  16. Chapter 11. Isolation and Primary Culture of Leydig Cells
  17. Chapter 12. Purification and Primary Culture of Leydig Cells
  18. Chapter 13. Preparation and Use of Sertoli Cell-Enriched Cultures from 18-Day-Old Rats
  19. Chapter 14. Two-Compartment Cultures of Sertoli Cells—Applications in Testicular Toxicology
  20. Chapter 15. Isolation, Separation, and Short-Term Culture of Spermatogenic Cells
  21. Chapter 16. Collection of Interstitial Fluid and Seminiferous Tubule Fluid from the Rat Testis
  22. Chapter 17. Isolation and Culture of Epididymal Epithelial Cells from Adult Rats
  23. Chapter 18. Evaluation of Protein Synthesis by the Epididymis
  24. Chapter 19. Utilizing Cryo Resources CellSoft Computer-Assisted Sperm Analysis System for Rat Sperm Motility Studies
  25. Chapter 20. Computer-Assisted Sperm Analysis of Rodent Epididymal Sperm Motility Using the Hamilton-Thorn Motility Analyzer
  26. Chapter 21. Methods for Evaluation of Rat Epididymal Sperm Morphology
  27. Chapter 22. Semen Analysis and Fertility Assessment in the Rabbit
  28. Chapter 23. General Techniques for Assessing Male Reproductive Potential in Human Field Studies
  29. Index