The Developing Human Brain

Growth and Adversities

Floyd H Gilles, Marvin D Nelson Jr

• Publisher: Mac Keith Press
• Year: 2012
• Print ISBN: 9781908316417
• eBook ISBN: 9781908316417
• Topic: Medicine
• Subtopic: Neurology

This book is about human brain development, focusing on the last half of gestation and the neonatal and infant periods. These periods bring the greatest risk for the acquisition of childhood functional neurologic deficits, including cerebral palsy, developmental delay and intellectual disability.Section 1 covers typical development, including growth in brain weight, ventricular surfaces, gyral development, myelinated tract development, magnetic resonance spectroscopy, and angiogenesis, all serving as reference points for section 2, which deals with common acquired brain abnormalities, some of which are often underemphasized or overlooked.The topics in section 2 include retrocerebellar cysts, abnormal events in fetal brain, white-matter abnormalities, lesions of gray and white matter, hemorrhage, ventriculomegaly and hydrocephalus, late expressions of fetal brain disease, and reactions of the developing brain to chronic disease. Between sections 1 and 2 is a chapter on embryonic and fetal physiologic reactions to external stimuli.Where appropriate, the authors have combined pathologic with neuroimaging examples to help the reader better understand the neuroimages that they encounter.Much of the information in the book is based on data from the National Collaborative Perinatal Project, still the only large autopsy survey of late fetal brain lesions.

Table of contents

• Contents
• Preface
• Acknowledgments
• 1 INTRODUCTION
• Section 1
• 2 BRAIN GROWTH
• 3 FETAL VENTRICULAR SIZE, SURFACES, ANDAPPENDAGES
• 4 GERMINAL TISSUE (S UBVENTRICULARZONE)
• 5 SURFACE CONFIGURATION—GYRALPATTERN DEVELOPMENT
• 6 MYELINATED TRACTS: GROWTH PATTERNS
• 7 DEVELOPING BRAIN IMAGING ANDMagnetic resonance SPECTROSCOPY
• 8 ANGIOGENESIS
• Section 2
• 9 DEVELOPMENTAL HUMAN FETALREACTIONS: AVOID, SQUINT, SCOWL,SNEER, AND PUCKER
• 10 BLAKE’S POUCH AND RETROCEREBELLARCYSTS: POSTERIOR FOSSA CYSTS
• 11 Developmental Central NervousSystem Aberration
• 12 Cerebral White Matter Abnormalities
• 13 Late Fetal and Perinatal BrainVascular Abnormalities andNecroses
• 14 FETAL AND NEONATAL INTRACRANIALHEMORRHAGE
• 15 VENTRICULOMEGALY, LARGEHEAD, MEGALENCEPHALY, ANDHYDROCEPHALUS
• 16 DEVELOPING BRAIN REACTIONS DURINGCHRONIC CHILDHOOD DISEASE
• 17 CONCLUDING REMARKS
• Index
• Colour plate