
- 542 pages
- English
- PDF
- Available on iOS & Android
About this book
Drug discovery and development process aims to make available medications that are safe and effective in improving the length and quality of life and relieving pain and suffering. However, the process is very complex, time consuming, resource intensive, requiring multi-disciplinary expertise and innovative approaches. There is a growing urgency to identify and develop more effective, efficient, and expedient ways to bring safe and effective products to the market. The drug discovery and development process relies on the utilization of relevant and robust tools, methods, models, and validated biomarkers that are predictive of clinical effects in terms of diagnosis, prevention, therapy, and prognosis. There is a growing emphasis on translational research, a bidirectional bench to the bedside approach, in an effort to improve the process efficiency and the need for further innovations. The authors in the book discuss the current and evolving state of drug discovery and development.
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Information
Table of contents
- Drug Discovery and Development - Present and Future
- Contents
- Preface
- 00a_Overview of Current Drug Discovery and Development with an Eye Towards the Future
- 00b_Part 1_ Current Status and Future Directions
- 01_Drug Discovery and Ayurveda: Win-Win Relationship Between Contemporary and Ancient Sciences
- 02_Evolutionary Biology and Drug Development
- 03_Novel Oncology Drug Development Strategies in the Era of Personalised Medicine
- 04_Drug Discovery into the 21st Century
- 04a_Part 2_ Models
- 05_Genetically Engineered Mouse Models in Preclinical Anti-Cancer Drug Development
- 06_Genetic Pharmacotherapy
- 07_Critical Human Hepatocyte-Based In Vitro Assays for the Evaluation of Adverse Drug Effects
- 08_The Use of In Vitro 3D Cell Models in Drug Development for Respiratory Diseases
- 08a_Part 3_ Tools, Methods, and Biomarkers
- 09_Chemical Biology: What is Its Role in Drug Discovery?
- 10_Towards Understanding Drugs on the Molecular Level to Design Drugs of Desired Profiles
- 11_De-Risking Drug Discovery Programmes Early with ADMET
- 12_Novel Approach to High Throughput Screening for Activators of Transcription Factors
- 13_Assessment of Cell Cycle Inhibitors by Flow Cytometry
- 14_Image-Based High-Content Screening in Drug Discovery
- 15_Recent Advances in Biotherapeutics Drug Discovery and Development
- 16_Drug Discovery by Aptamers in Protozoan Infectious Diseases
- 17_Streamlining ICH Q6B Analytical Testing of Biotherapeutics
- 18_Biomarkers in Drug Development: A Useful Tool but Discrepant Results May Have a Major Impact
- 18a_Part 4_ Drug Delivery
- 19_Nanotechnology Based Targeted Drug Delivery: Current Status and Future Prospects for Drug Development
- 20_Silver Nanoparticles – Universal Multifunctional Nanoparticles for Bio Sensing, Imaging for Diagnostics and Targeted Drug Delivery for Therapeutic Applications
- 21_Mesenchymal Stem Cells as Vehicles for Targeted Therapies