Hypoxia and Human Diseases

Jing Zheng, Chi Zhou, Jing Zheng, Chi Zhou

• Publisher: IntechOpen
• Year: 2017
• Print ISBN:
  9789535128953
• eBook ISBN:
  9789535173342
• Topic: Médecine
• Subtopic: Médecine pulmonaire et thoracique

This book contains a total of 21 chapters, each of which was written by experts in the corresponding field. The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders. This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners, and practicing clinicians in the fields of high altitude biology, cardiovascular biology and medicine, tumor oncology, obstetrics, pediatrics, and orthodontics and for others who may be interested in hypoxia.

Table of contents

• Hypoxia and Human Diseases
• Contents
• Preface
• Chapter 1 The Multifaceted Role of Hypoxia‐Inducible Factor 1 (HIF1) in Lipid Metabolism
• Chapter 2 Hypoxic Upregulation of ARNT (HIF-1β): A Cell-Specific Attribute with Clinical Implications
• Chapter 3 The Hypoxia-Reoxygenation Injury Model
• Chapter 4 Vascular Smooth Muscle as an Oxygen Sensor: Role of Elevation of the [Na+]i/[K+]i
• Chapter 5 Hypoxia in Mesenchymal Stem Cell
• Chapter 6 Cardiovascular Adaptation to High-Altitude Hypoxia
• Chapter 7 Arterial Oxygen Saturation During Ascent to 5010 m: Heart Rate and AMS Scores
• Chapter 8 Hypoxia-Induced Molecular and Cellular Changes in the Congenitally Diseased Heart: Mechanisms and Strategies of Intervention
• Chapter 9 Adaptations to Chronic Hypoxia Combined with Erythropoietin Deficiency in Cerebral and Cardiac Tissues
• Chapter 10 Hypothermia in Stroke Therapy: Systemic versus Local Application
• Chapter 11 Hypoxia and Pulmonary Hypertension
• Chapter 12 Stage-Specific Effects of Hypoxia on Interstitial Lung Disease
• Chapter 13 Hypoxia Modulates the Adenosinergic Neural Network
• Chapter 14 The HIF System Response to ESA Therapy in CKD‐Anemia
• Chapter 15 Role of the Hypoxia-Inducible Factor in Periodontal Inflammation
• Chapter 16 Interplay between Hypoxia, Inflammation and Adipocyte Remodeling in the Metabolic Syndrome
• Chapter 17 Epigenetic Programming of Cardiovascular Disease by Perinatal Hypoxia and Fetal Growth Restriction
• Chapter 18 The Critical Role of Hypoxia in Tumor-Mediated Immunosuppression
• Chapter 19 Cross‐Talk Between Hypoxia and the Tumour via Exosomes
• Chapter 20 A Novel Hypoxia Imaging Endoscopy System
• Chapter 21 Hypoxia and its Emerging Therapeutics in Neurodegenerative, Inflammatory and Renal Diseases