Unique Aspects of Anti-cancer Drug Development

Jolanta Natalia Latosinska, Magdalena Latosinska, Jolanta Natalia Latosinska, Magdalena Latosinska

• Publisher: IntechOpen
• Year: 2017
• Print ISBN: 9789535133476
• eBook ISBN: 9789535147398
• Topic: Physical Sciences
• Subtopic: Physics
• Index: Physics

The evidence of cancer in humans, animals and plant species suggests that it is as old as multicellular life on Earth. Why is it so difficult to understand and fight? Because cancer begins from the organism's own mutated single cell focused on its own survival. It would be naive to expect that cancer could be ever entirely eliminated, but there is still hope for finding effective treatments. The book is to give a view of selected aspects of cancer like its spread in nature, novel anticancer drugs based on Chinese herbs or birch bark, novel promising targets of annexins and kinases and progress in immunotherapy. It is our hope that you will find in this book interesting, inspiring and stimulating information concerning cancer research.

Table of contents

• Unique Aspects of Anti-Cancer Drug Development
• Contents
• Preface
• Chapter 1 Introductory Chapter: Having a Brain is Not Necessary to Get Cancer… but Indispensable to Fight It
• Chapter 2 Application of Computer Modeling to Drug Discovery: Case Study of PRK1 Kinase Inhibitors as Potential Drugs in Prostate Cancer Treatment
• Chapter 3 Annexin Proteins: Novel Promising Targets for Anticancer Drug Development
• Chapter 4 Immunotherapy in Pediatric Acute Leukemia: A Novel Magic Bullet or an Illusory Hope?
• Chapter 5 Lupan-Skeleton Pentacyclic Triterpenes with Activity against Skin Cancer: Preclinical Trials Evolution
• Chapter 6 Recent Progress on the Molecular Mechanisms of Anti-invasive and Metastatic Chinese Medicines for Cancer Therapy