eBook - PDF

Tyrosine Kinases as Druggable Targets in Cancer

Name: Tyrosine Kinases as Druggable Targets in Cancer
ISBN: 9781839622199

Huan Ren,

134 pages
English
PDF
Available on iOS & Android

eBook - PDF

Tyrosine Kinases as Druggable Targets in Cancer

Huan Ren,

About this book

Protein tyrosine kinase (PTK) deregulation contributes to growth of cancer and many other diseases. The development of small-molecule tyrosine kinase inhibitors (TKIs) that target the deregulated PTKs, such as epidermal growth factor receptor (EGFR) in non-small-cell lung cancer (NSCLC) and Bcr-ABL in chronic myeloid leukemia (CML), has revolutionized disease management. In this book, we examine a few aspects of PTKs and cancer, considering efficacy, predictive markers to therapeutic response, limitations, and future directions in TKI treatment. In this rapidly evolving field, overcoming therapeutic resistance is most challenging, and multi-targeting directs the next-generation TKIs and combination therapy as ongoing strategies in cancer treatment.

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Yes, you can access Tyrosine Kinases as Druggable Targets in Cancer by Huan Ren in PDF and/or ePUB format, as well as other popular books in Medicine & Oncology. We have over one million books available in our catalogue for you to explore.