Applied Organic Chemistry
eBook - ePub

Applied Organic Chemistry

Reaction Mechanisms and Experimental Procedures in Medicinal Chemistry

  1. English
  2. ePUB (mobile friendly)
  3. Available on iOS & Android
eBook - ePub

Applied Organic Chemistry

Reaction Mechanisms and Experimental Procedures in Medicinal Chemistry

About this book

An indispensable guide for all synthetic chemists who want to learn about the most relevant reactions and reagents employed to synthesize important heterocycles and drugs!

The synthesis of natural products, bioactive compounds, pharmaceuticals, and drugs is of fundamental interest in modern organic chemistry. New reagents and reaction methods towards these molecules are being constantly developed. By understanding the mechanisms involved and scope and limitations of each reaction applied, organic chemists can further improve existing reaction protocols and develop novel efficient synthetic routes towards frequently used drugs, such as Aspirin or Penicillin.

Applied Organic Chemistry provides a summary of important (name) reactions and reagents applied in modern organic chemistry and drug synthesis. It covers rearrangement, condensation, olefination, metathesis, aromatic electrophilic substitutions, Pd-catalyzed C-C bond forming reactions, multi-component reactions, as well as oxidations and reductions. Each chapter is clearly structured, providing valuable information on reaction details, step-by-step mechanism, experimental procedures, applications, and (patent) references. By providing mechanistic information and representative experimental procedures, this book is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.

  • Hot Topic: Reviews important classes of organic reactions (incl. name reactions) and reagents in medicinal chemistry.
  • Useful: Provides information on reaction details, common reagents, and functional group transformations used to synthesize natural products, bioactive compounds, drugs, and pharmaceuticals, e.g. Aspirin, Penicillin.
  • Unique: For every reaction the mechanism is explained step by step, and representative experimental procedures are given, unlike most books in this area.
  • User-friendly: Chapters are clearly structured making it easy for the reader to compare different reactions.

Applied Organic Chemistry is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.

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Information

Publisher
Wiley-VCH
Year
2020
Print ISBN
9783527347858
eBook ISBN
9783527828173

Table of contents

  1. Cover
  2. Table of Contents
  3. Applied Organic Chemistry
  4. Copyright
  5. Preface
  6. About the Book
  7. About the Author
  8. Acknowledgments
  9. List of Abbreviations
  10. 1 Rearrangement Reactions
  11. 2 Condensation Reaction
  12. 3 Olefination, Metathesis, and Epoxidation Reactions
  13. 4 Miscellaneous Reactions
  14. 5 Aromatic Electrophilic Substitution Reactions
  15. 6 Pd‐Catalyzed CC Bond‐Forming Reactions
  16. 7 Multicomponent Reaction
  17. 8 Oxidations and Reductions
  18. 9 Nomenclature and Application of Heterocyclic Compounds
  19. 10 Synthesis of Some Heterocyclic Compounds Using Named Reactions
  20. 11 Protection and Deprotection of Common Functional Groups
  21. 12 Amino Acids and Peptides
  22. 13 Functional Group Transformation
  23. 14 Synthesis of Some Drug Molecules
  24. 15 Common Laboratory Methods
  25. 16 Common Reagents in Organic Synthesis
  26. Appendix A: Appendix AList of Medicines (Partial) and Nutrients
  27. Index
  28. End User License Agreement

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