Fast Facts: Acute and Recurrent Pancreatitis

Using Evidence to Support Treatment

Enrique de-Madaria, Matthias Löhr, E. de-Madaria, M. Löhr

• Publisher: S. Karger
• Year: 2020
• Print ISBN: 9783318066241
• eBook ISBN: 9783318066258
• Topic: Medicine
• Subtopic: Gastroenterology & Hepatology

Acute pancreatitis (AP) is one of the most common disorders of the gastrointestinal tract to result in hospitalization. Although most patients with AP will experience an uneventful disease course, those that develop moderate-to-severe AP can be challenging to manage. Rapid recognition, accurate diagnosis and prediction of severity, together with appropriate treatment, are therefore key in achieving the best outcomes for patients and for preventing subsequent episodes of AP. Written by two pancreatologists with extensive experience of managing patients with AP as well as in clinical research, 'Fast Facts: Acute and Recurrent Pancreatitis' provides a comprehensive, evidence-based guide to: - The pathophysiology and etiology of AP - Fundamentals of diagnosis - Predicting the likely severity of an episode of AP - Monitoring and managing complications in the early and later stages of disease - Preventing recurrence This book will be of interest to all those who may be involved in the care of patients with AP, including internal medicine specialists, gastroenterologists, intensive care specialists, surgeons and endoscopists.

Index

AP = acute pancreatitis

abdominal compartment syndrome (ACS) 48, 72–3

acinar cells 9, 10

acute abdomen 30–1

age 15, 33

alcohol-related AP 15, 19, 82

amylase 28–9, 30–1

analgesia 52

anatomy 10

antibiotics 54

anticoagulants 76

APACHE-II score 37, 38

Atlanta classification (RAC) 35, 41–6

autoimmune pancreatitis 23, 79, 80

autophagy blockade 11–12

Balthazar score 35

bile duct compression 27, 62

biliary AP 15, 17, 27, 49, 54–5, 79–81

BISAP score 37–8

blood tests 28–9, 34, 49

Bryant’s sign 28

BUN 34

C-reactive protein (CRP) 34

calcium levels 49

calcium signaling 10

cancer 19

cardiac failure 44

CEL/CELP recombination 22

children 20

cholangitis 27, 49, 55

cholecystectomy 79–81

chronic pancreatitis 19, 21, 84

classification of severity 33, 45–6

complications

fluid collections 13, 42–3, 60–9

late 83–4

local 13, 34, 41–3, 72–7, 81

organ failure 13, 35–7, 43–5, 48–9, 72

SIRS 13, 33, 34–5, 36, 38

CPA1 mutations 22

CT scans 29, 34, 41, 42, 62, 63, 74, 79

CTFR mutations 22

CTRC mutations 22

Cullen’s sign 28

definitions

AP 9, 27

complications 41–5

recurrent AP 9

severity 33, 45–6

diabetes mellitus 49, 53, 83

diagnosis 27–32, 79

fluid collections 61–3, 65

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Table of contents

• Cover
• Title Page
• Copyright
• Contents
• List of abbreviations
• Introduction
• Pathophysiology
• Epidemiology and etiology
• Diagnosis
• Prognosis
• Definitions for complications and severity classification
• Early management
• Management of symptomatic collections
• Management of other local complications
• Preventing recurrence and monitoring for late complications after acute pancreatitis
• Useful resources
• Index