Computational Methods for Mass Spectrometry Proteomics
eBook - PDF

Computational Methods for Mass Spectrometry Proteomics

  1. English
  2. PDF
  3. Available on iOS & Android
eBook - PDF

Computational Methods for Mass Spectrometry Proteomics

About this book

Proteomics is the study of the subsets of proteins present in different parts of an organism and how they change with time and varying conditions. Mass spectrometry is the leading technology used in proteomics, and the field relies heavily on bioinformatics to process and analyze the acquired data.   Since recent years have seen tremendous developments in instrumentation and proteomics-related bioinformatics, there is clearly a need for a solid introduction to the crossroads where proteomics and bioinformatics meet.

Computational Methods for Mass Spectrometry Proteomics describes the different instruments and methodologies used in proteomics in a unified manner. The authors put an emphasis on the computational methods for the different phases of a proteomics analysis, but the underlying principles in protein chemistry and instrument technology are also described. The book is illustrated by a number of figures and examples, and contains exercises for the reader. Written in an accessible yet rigorous style, it is a valuable reference for both informaticians and biologists.

Computational Methods for Mass Spectrometry Proteomics is suited for advanced undergraduate and graduate students of bioinformatics and molecular biology with an interest in proteomics. It also provides a good introduction and reference source for researchers new to proteomics, and for people who come into more peripheral contact with the field.

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Yes, you can access Computational Methods for Mass Spectrometry Proteomics by Ingvar Eidhammer,Kristian Flikka,Lennart Martens,Svein-Ole Mikalsen in PDF and/or ePUB format, as well as other popular books in Medicine & Immunology. We have over one million books available in our catalogue for you to explore.

Information

Year
2008
Print ISBN
9780470512975
eBook ISBN
9780470724293
Edition
1
Subtopic
Immunology

Table of contents

  1. Computational Methods for Mass Spectrometry Proteomics
  2. Contents
  3. Preface
  4. Acknowledgements
  5. 1 Protein, proteome, and proteomics
  6. 2 Protein separation – 2D gel electrophoresis
  7. 3 Protein digestion
  8. 4 Peptide separation – HPLC
  9. 5 Fundamentals of mass spectrometry
  10. 6 Mass spectrometry – MALDI-TOF
  11. 7 Protein identification and characterization by MS
  12. 8 Tandem MS or MS/MS analysis
  13. 9 Fragmentation models
  14. 10 Identification and characterization by MS/MS
  15. 11 Spectral comparisons
  16. 12 Sequential comparison – de novo sequencing
  17. 13 Database searching for de novo sequences
  18. 14 Large-scale proteomics
  19. 15 Quantitative MS-based proteomics
  20. 16 Peptides to proteins
  21. 17 Top-down proteomics
  22. 18 Standards
  23. Bibliography
  24. Index