
Computational Methods for Mass Spectrometry Proteomics
- English
- PDF
- Available on iOS & Android
Computational Methods for Mass Spectrometry Proteomics
About this book
Computational Methods for Mass Spectrometry Proteomics describes the different instruments and methodologies used in proteomics in a unified manner. The authors put an emphasis on the computational methods for the different phases of a proteomics analysis, but the underlying principles in protein chemistry and instrument technology are also described. The book is illustrated by a number of figures and examples, and contains exercises for the reader. Written in an accessible yet rigorous style, it is a valuable reference for both informaticians and biologists.
Computational Methods for Mass Spectrometry Proteomics is suited for advanced undergraduate and graduate students of bioinformatics and molecular biology with an interest in proteomics. It also provides a good introduction and reference source for researchers new to proteomics, and for people who come into more peripheral contact with the field.
Frequently asked questions
- Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
- Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Information
Table of contents
- Computational Methods for Mass Spectrometry Proteomics
- Contents
- Preface
- Acknowledgements
- 1 Protein, proteome, and proteomics
- 2 Protein separation – 2D gel electrophoresis
- 3 Protein digestion
- 4 Peptide separation – HPLC
- 5 Fundamentals of mass spectrometry
- 6 Mass spectrometry – MALDI-TOF
- 7 Protein identification and characterization by MS
- 8 Tandem MS or MS/MS analysis
- 9 Fragmentation models
- 10 Identification and characterization by MS/MS
- 11 Spectral comparisons
- 12 Sequential comparison – de novo sequencing
- 13 Database searching for de novo sequences
- 14 Large-scale proteomics
- 15 Quantitative MS-based proteomics
- 16 Peptides to proteins
- 17 Top-down proteomics
- 18 Standards
- Bibliography
- Index