Solid-Phase Organic Synthesis
About this book
Solid-Phase Organic Synthesis Edited by Kevin Burgess, Texas A & M University Efficient, high-throughput chemistry is now the focus of many research laboratories. Solid-phase organic syntheses are central to many of these combinatorial and parallel screening methodologies. Consequently, they have been a major scientific theme of the 1990s and promise to remain prominent for the first part of the new millennium. Indeed, a bewildering number of papers have entered the literature on this topic; some report minor modifications enabling transformation of solution-phase methods to a solid support, while others report major innovations. Solid-Phase Organic Synthesis collects, highlights, and critiques some of the key developments in the field. Leading practitioners explain different perspectives on diverse aspects of the area. Specific topics covered include:
* Syntheses of guanidines
* Palladium-catalyzed C-C bond forming reactions
* S_nAr reactions for the formation of heterocycles
* Sequence-specific arylalkyne oligomers
* Resin-supported capture agents and other reagents
* Synthesis on pins
* Monitoring of supported reactions using IR
* Solid-phase syntheses of natural product derivatives
Of related interest. Combinatorial Chemistry and Molecular Diversity in Drug Discovery Eric M. Gordon and James F. Kerwin 1998 (0-471-15518-7) 544 pp. Combinatorial Chemistry Synthesis and Application Stephen R. Wilson and Anthony W. Czarnik 1997 (0-471-12687-X) 288 pp.
Frequently asked questions
- Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
- Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Information
Table of contents
- CONTENTS
- PREFACE
- CONTRIBUTORS
- 1 SOLID-PHASE SYNTHESES OF GUANIDINES
- 2 PALLADIUM-CATALYZED CARBON-CARBON BOND FORMATION ON SOLID SUPPORT
- 3 BENZOFUSED HETEROCYCLES VIA SOLID-PHASE S[sub(N)]AR REACTIONS
- 4 SOLID-PHASE SYNTHESIS OF SEQUENCE-SPECIFIC PHENYLACETYLENE OLIGOMERS
- 5 POLYMER-ASSISTED SOLUTION-PHASE METHODS FOR CHEMICAL LIBRARY SYNTHESIS
- 6 SOLID-PHASE ORGANIC SYNTHESIS ON RADIATION-GRAFTED POLYMER SURFACES: APPLICATION OF SYNPHASE CROWNS TO MULTIPLE PARALLEL SYNTHESES
- 7 VIBRATIONAL SPECTROSCOPY FOR OPTIMIZATION OF SOLID-PHASE ORGANIC SYNTHESES
- 8 RECENT ADVANCES IN SOLID-PHASE SYNTHESIS OF NATURAL PRODUCTS
- INDEX
