Advances in Cancer Signal Transduction and Therapy
eBook - ePub

Advances in Cancer Signal Transduction and Therapy

  1. English
  2. ePUB (mobile friendly)
  3. Available on iOS & Android
eBook - ePub

Advances in Cancer Signal Transduction and Therapy

About this book

Cancer is driven by numerous genetic and epigenetic changes occurring at the cellular level.These changes drive normal cells to proliferate and escape processes thatusually regulate their survival and migration. Many of these alterations areoften associated with signaling pathways which regulate cell growth anddivision, cell death, survival, invasion and metastasis, and angiogenesis.Almost all cancer cells show high expression of signaling components includinggrowth factor receptor tyrosine kinases (RTKs), small GTPases, serine/threoninekinases, cytoplasmic tyrosine kinases, lipid kinases, estrogen receptor, activation of transcription factors Myc and NF-?B, etc. Updated knowledge aboutthese signaling components is highly desirable for researchers involved indeveloping therapies against cancer.Signal TransductionResearch for Cancer Therapy covers advancements in research on the signalingpathways in the human body, especially in some types of cancers, such asbreast cancer, pancreatic cancer and colon cancer. Keyfeatures of this volume include 8 focused topical reviews on signaling pathwaysin a specific cancer type, coverage of multiple cancer types (breast cancer, colon cancer, hepatocellular cancer, multiple myeloma, acute myeloid leukemia, and pancreatic cancer), and coverage of a wide array of signaling pathways (bothreceptor mediated and non receptor mediated pathways). Thisvolume is essential reading for researchers in pharmaceutical R&D andpostgraduate research programs in pharmacology and allied disciplines.Clinicians involved in oncology will also benefit from the information providedin the chapters.

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Yes, you can access Advances in Cancer Signal Transduction and Therapy by Manoj K. Pandey,Vijay P. Kale, Manoj K. Pandey, Vijay P. Kale in PDF and/or ePUB format, as well as other popular books in Medicine & Oncology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Bentham Science Publishers
Year
2020
Print ISBN
9789811458095
eBook ISBN
9789811458118
Topic
Medicine
Subtopic
Oncology

Table of contents

  1. Welcome
  2. Table of Content
  3. Title
  4. BENTHAM SCIENCE PUBLISHERS LTD.
  5. PREFACE
  6. LIST OF CONTRIBUTORS
  7. Wnt Signaling in Breast Cancer Oncogenesis, Development and Progression
  8. CXCR4 Signaling and its Impact on Tumor Progression and Metastasis in Breast Cancer
  9. Epidermal Growth Factor Receptor Signaling in Colon Cancer
  10. Targeting the PI3K/AKT/mTOR Signaling Pathway in Hepatocellular Carcinoma: Current State and Future Trends
  11. MAPK Signaling Pathway: A Central Target in Pancreatic Cancer Therapeutics
  12. Role of NF-κB Activation in Multiple Myeloma and Other Hematological Malignancies
  13. Bruton’s Tyrosine Kinase Signaling and Advancement in Multiple Myeloma Therapy
  14. The Tumor Microenvironment Mediated Signaling Pathways in the Progression of Acute Myeloid Leukemia