
Pathology of Genetically Engineered and Other Mutant Mice
- English
- PDF
- Available on iOS & Android
Pathology of Genetically Engineered and Other Mutant Mice
About this book
An updated and comprehensive reference to pathology in every organ system in genetically modified mice
The newly revised and thoroughly updated Second Edition of Pathology of Genetically Engineered and Other Mutant Mice delivers a comprehensive resource for pathologists and biomedical scientists tasked with identifying and understanding pathologic changes in genetically modified mice. The book is organized by body system, includes descriptions and explanations of a wide range of findings, as well as hundreds of color photographs illustrating both common and rare lesions that may be found in genetically engineered and wild type mice.
The book is written by experienced veterinary and medical pathologists working in veterinary medical colleges, medical colleges, and research institutes. Covering the latest discoveries in mouse pathology resulting from advancements in biotechnology research over the last 30 years, this singular and accessible resource is a must-read for veterinary and medical pathologists and researchers working with genetically engineered and other mice.
Readers will also benefit from:
- A thorough introduction to mouse pathology and mouse genetic nomenclature, as well as databases useful for analysis of mutant mice
- An exploration of concepts related to validating animal models, including the Cinderella Effect
- Practical discussions of basic necropsy methods and grading lesions for computational analyses
- Concise diagnostic approaches to the respiratory tract, the oral cavity and GI tract, the cardiovascular system, the liver and pancreas, the skeletal system, and other tissues
As a one-stop and up to date reference on mouse pathology, Pathology of Genetically Engineered and Other Mutant Mice is an essential book for veterinary and medical pathologists, as well as for scientists, researchers, and toxicologists whose work brings them into contact with genetically modified mice.
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Information
Table of contents
- Cover
- Title Page
- Copyright Page
- Contents
- List of Contributors
- Preface and Acknowledgments
- Chapter 1 Introduction to Mouse Pathology
- Chapter 2 The Mouse Online: Open Mouse Biology and Pathology Data Resources for Biomedical Research:
- Chapter 3 Mouse Genetic Nomenclature: The Underpinning of Mouse Genetics
- Chapter 4 Discovering and Validating Mouse Models of Human Diseases: The Cinderella Effect
- Chapter 5 Embryos, Placentas, and Neonates
- Chapter 6 Ciliopathies
- Chapter 7 Hematopoietic and Lymphoid Tissues
- Chapter 8 Mouse Hematolymphoid Neoplasms
- Chapter 9 Immunodeficient and Humanized Mice
- Chapter 10 Skin, Hair, and Nails
- Chapter 11 Mammary Gland
- Chapter 12 The Respiratory Tract
- Chapter 13 The Gastrointestinal Tract
- Chapter 14 Cardiovascular System
- Chapter 15 Liver and Pancreas
- Chapter 16 Neuromuscular System
- Chapter 17 Endocrine System
- Chapter 18 Kidney and Urinary Bladder
- Chapter 19 Female Reproductive System
- Chapter 20 Male Reproductive System
- Chapter 21 Nervous System
- Chapter 22 Eye and Ear
- Chapter 23 Bones and Teeth
- Index
- EULA