
Algorithms for Sample Preparation with Microfluidic Lab-on-Chip
- 250 pages
- English
- PDF
- Available on iOS & Android
Algorithms for Sample Preparation with Microfluidic Lab-on-Chip
About this book
Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip bridges the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips.Technical topics discussed in the book include: - Basics of digital and flow-based microfluidic lab-on-chip
- Comprehensive review of state-of-the-art sample preparation algorithms
- Sample-preparation algorithms for digital microfluidic lab-on-chip
- Sample-preparation algorithms for flow-based microfluidic lab-on-chip
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Information
Table of contents
- Front Cover
- Half Title Page
- RIVER PUBLISHERS SERIES IN BIOMEDICALENGINEERING
- Title Page
- Copyright Page
- Contents
- Preface
- List of Figures
- List of Tables
- List of Abbreviations
- Chapter 1 - Introduction
- Chapter 2 - Sample Preparation with Microfluidic Biochips: A Review
- Chapter 3 - Multiple Dilution Sample Preparation on Digital Microfluidic Biochips
- Chapter 4 - Efficient Generation of Dilution Gradients with Digital Microfluidic Biochips
- Chapter 5 - Concentration-Resilient Mixture Preparation
- Chapter 6 - Dilution and Mixing Algorithms for Flow-based Microfluidic Biochips
- Chapter 7 - Storage-Aware Algorithms for Dilution and Mixture Preparation with Flow-Based Lab-on-Chip
- Chapter 8 - Conclusion and Future Directions
- Bibliography
- Index
- About the Authors
- Back Cover