Proteostasis integrates biological pathways controlling biogenesis, trafficking, folding, and degradation of proteins. This book focuses on two protein breakdown/degradation processes (proteolysis), which are part of a normally functioning proteostatic system: the ubiquitin-proteasome system and autophagy.

Chapter 2 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.

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Yes, you can access Proteostasis and Proteolysis by Niki Chondrogianni, Elah Pick, Anna Gioran, Niki Chondrogianni,Elah Pick,Anna Gioran in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biochemistry in Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Year

Print ISBN

eBook ISBN

Edition

Topic

Biological Sciences

Subtopic

Biochemistry in Medicine

Index

Biological Sciences

Cover Page
Half Title Page
Series Page
Title Page
Copyright Page
Contents
Preface
Contributors
The Editors
1 Ribosomal Pauses During Translation and Proteostasis
2 Protein Folding and Misfolding: Deciphering Mechanisms of Age-Related Diseases
3 Transcriptional Regulation of Proteostatic Mechanisms
4 Micrornas as Central Regulators of Adult Myogenesis and Proteostasis Loss in Skeletal Muscle Aging
5 Mrna Granules and Proteostasis in Aging and Age-Related Diseases
6 Phospholipids and the Unfolded Protein Response
7 Ubiquitin Ligases Involved in Progeroid Syndromes and Age-Associated Pathologies
8 Role of Sumoylation in Neurodegenerative Diseases and Inflammation
9 Nedd8 and Oxidative Stress
10 Structure, Function and Regulators of the 20s Proteasome
11 Cellular Responses to Proteasome Impairment
12 Proteasome Fate in Aging and Proteinopathies
13 The Proteasomal System in Cancer
14 Proteostasis and Skin Aging
15 Reactive Oxygen Species and Protein Homeostasis in Skeletal Muscle Regeneration
16 Protein Degradation in Cardiac Health and Disease
17 Autophagy in Aging and Oxidative Stress
18 Autophagy in Aging and Longevity Exemplified by the Aging Heart
Index

About this book

Frequently asked questions

Information

Table of contents