Model-based design of optimal reactors for (bio)pharmaceutical manufacturing
eBook - PDF

Model-based design of optimal reactors for (bio)pharmaceutical manufacturing

,
  1. 194 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Model-based design of optimal reactors for (bio)pharmaceutical manufacturing

,

About this book

Die Pharmaindustrie durchläuft einen tiefgreifenden Wandel, der durch eine technologische Revolution der Herstellungsverfahren getrieben wird. Im Mittelpunkt des Umbruches steht das Quality by-Design, das von der amerikanischen Food and Drug Administration initiiert wurde, um die Entwicklung zukßnftiger Fertigungsprozesse fßr nieder- und hochmolekulare Medikamente zu steuern. Basierend auf den Anforderungen der Industrie und unter Berßcksichtigung der aktuellen Fachliteratur spielen systemverfahrenstechnische Konzepte (engl. Process Systems Engineering) bei der Implementierung von Qualityby-Design-Methoden eine entscheidende Rolle.

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Information

Publisher
Cuvillier Verlag
Year
2019
Print ISBN
9783736971172
eBook ISBN
9783736961173
Edition
1

Table of contents

  1. 1. INTRODUCTION
  2. 2. METHODOLOGY
  3. 3. A SYSTEMATIC REACTOR DESIGN APPROACH FOR THESYNTHESIS OF ACTIVE PHARMACEUTICAL INGREDIENTS
  4. 4. MODEL-BASED DESIGN OF AN OPTIMAL REACTOR FOR ENZYMECATALYZED CROSS-CARBOLIGATION
  5. 5. ROBUST DYNAMIC OPTIMIZATION OF ENZYME-CATALYZEDCARBOLIGATION
  6. 6. MULTISCALE BIOREACTOR DESIGN BASED ON DYNAMIC FLUXBALANCE ANALYSIS
  7. 7. CONCLUSIONS AND FUTURE DIRECTIONS
  8. 8. APPENDIX TO CHAPTER 3
  9. 9. APPENDIX TO CHAPTER 5