Genome Editing in Drug Discovery
eBook - PDF

Genome Editing in Drug Discovery

  1. English
  2. PDF
  3. Available on iOS & Android
eBook - PDF

About this book

GENOME EDITING IN DRUG DISCOVERY

A practical guide for researchers and professionals applying genome editing techniques to drug discovery

In Genome Editing in Drug Discovery, a team of distinguished biologists delivers a comprehensive exploration of genome editing in the drug discovery process, with coverage of the technology's history, current issues and techniques, and future perspectives and research directions. The book discusses techniques for disease modeling, target identification with CRISPR, safety studies, therapeutic editing, and intellectual property issues.

The safety and efficacy of drugs and new target discovery, as well as next-generation therapeutics are also presented.

Offering practical suggestions for practitioners and academicians involved in drug discovery, Genome Editing in Drug Discovery is a fulsome treatment of a technology that has become part of nearly every early step in the drug discovery pipeline. Selected contributions also include:

  • A thorough introduction to the applications of CRISPRi and CRISPRa in drug discovery
  • Comprehensive explorations of genome-editing applications in stem cell engineering and regenerative medicine
  • Practical discussions of the safety aspects of genome editing with respect to immunogenicity and the specificity of CRISPR-Cas9 gene editing
  • In-depth examinations of critical socio-economic and bioethical challenges in the CRISPR-Cas9 patent landscape

Perfect for academic researchers and professionals in the biotech and pharmaceutical industries, Genome Editing in Drug Discovery will also earn a place in the libraries of medicinal chemists, biochemists, and molecular biologists.

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Yes, you can access Genome Editing in Drug Discovery by Marcello Maresca, Sumit Deswal, Marcello Maresca,Sumit Deswal in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Wiley
Year
2022
Print ISBN
9781119671343
eBook ISBN
9781119671381

Table of contents

  1. Cover
  2. Title Page
  3. Copyright Page
  4. Contents
  5. Preface
  6. List of Abbreviations
  7. List ofĀ Contributors
  8. Part 1 Introduction toĀ Drug Discovery andĀ Genome Editing Methods
  9. Part 2 Genome Editing in Disease Modeling
  10. Part 3 Genome Editing in Target Identification and Validation
  11. Part 4 Therapeutic Genome Editing
  12. Part 5 Intellectual Property Aspects and Future Prospects
  13. Index
  14. EULA